Evidence map›Paper›PMID 35276976›Full record

ArticleNutrients2022

The Associations of Erythrocyte Fatty Acids with Whole Blood Mineral Elements in Children.

Zhi Huang, Xing Liu, Ziming Li, Luwei Cui, Candi Liu, Weifeng Wang, Yuming Hu, Bo Chen

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Zhi HuangKey Laboratory of Phytochemical R & D of Hunan Province, School of Chemistry & Chemical Engineering, Hunan Normal University, Lu Mountain Road No. 286, Changsha 410081, China.
Xing LiuKey Laboratory of Phytochemical R & D of Hunan Province, School of Chemistry & Chemical Engineering, Hunan Normal University, Lu Mountain Road No. 286, Changsha 410081, China.
Ziming LiThe Department of Toxicology, Hunan Provincial Center for Disease Control and Prevention, Furong Road No. 450, Changsha 410005, China.
Luwei CuiThe Department of Toxicology, Hunan Provincial Center for Disease Control and Prevention, Furong Road No. 450, Changsha 410005, China.
Candi LiuKey Laboratory of Phytochemical R & D of Hunan Province, School of Chemistry & Chemical Engineering, Hunan Normal University, Lu Mountain Road No. 286, Changsha 410081, China.
Weifeng WangThe Department of Toxicology, Hunan Provincial Center for Disease Control and Prevention, Furong Road No. 450, Changsha 410005, China.
Yuming HuThe Department of Toxicology, Hunan Provincial Center for Disease Control and Prevention, Furong Road No. 450, Changsha 410005, China.ORCID 0000-0003-2542-016X
Bo ChenKey Laboratory of Phytochemical R & D of Hunan Province, School of Chemistry & Chemical Engineering, Hunan Normal University, Lu Mountain Road No. 286, Changsha 410081, China.
Hunan Provincial Center for Disease Control and Prevention · CNHunan Normal University · CNHunan University · CN

Funding

the Aid Program for S&T innovation research team in higher education institutions,the construction program of key disciplines of Hunan Province 2015JC1001the National Natural Science Foundation of China 21775040, 21775041, 21575040
6 · The paper itself

Abstract

Background. Minerals play important biological roles in lipid metabolism. The primary aim of this study was to examine the relationships between erythrocyte fatty acids (FAs) levels with whole blood mineral elements concentrations among Chinese children. Methods. A cross-sectional study was conducted. A total of 435 children aged 4−7 years were recruited. Whole blood mineral elements were determined by atomic absorption spectrometry and erythrocyte FAs composition by gas chromatography-mass spectrometer. Results. There were direct correlations between Zn and C18:2n-6 (FDR corrected p = 0.019), total n-6 PUFAs (FDR corrected p = 0.034), and total PUFAs (FDR corrected p = 0.034). Direct correlations were found between whole blood Zn and C18:1n-9 (FDR corrected p = 0.035), C24:1n-9 (FDR corrected p = 0.023), total MUFAs (FDR corrected p = 0.023), and C18:2n-6 (FDR corrected p = 0.048) in the Cu < P50 group. In the Cu ≥ P50 group, Mg was inversely related to most FAs (All FDR corrected p < 0.05). In the Zn < P50 group, Cu was directly related to C24:1n-9, total MUFAs, C20:5n-3, C22:6n-3, total n-3 PUFAs, C20:4n-6, total n-6 PUFAs, total PUFAs, and total FAs (All FDR corrected p < 0.05). Conclusions. Whole blood Cu and Zn levels were directly linked to several FAs levels in the erythrocytes of children. The interactions of Mg, Cu, and Zn with fatty acids may affect FA metabolism, in which Mg influences FA absorption.

Indexed as

Fatty AcidsMineralsChildChild, PreschoolCross-Sectional StudiesErythrocytesGas Chromatography-Mass SpectrometryHumansFatty AcidsMineralschildrenerythrocytefatty acidsmineral elements

Identifiers

PMID35276976
PMCPMC8838319
OpenAlexW4210789067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.