Evidence map›Paper›PMID 35276947›Full record

ArticleNutrients2022

Taiwanese Vegetarians Are Associated with Lower Dementia Risk: A Prospective Cohort Study.

Jui-Hsiu Tsai, Ching-Feng Huang, Ming-Nan Lin, Chiao-Erh Chang, Chia-Chen Chang, Chin-Lon Lin

Abstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  4. Article
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  6. Review
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  8. Article
  9. Diets to promote healthy brain ageing.Nature reviews. Neurology · 2025
    Review
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  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jui-Hsiu TsaiDepartment of Psychiatry, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi 622, Taiwan.ORCID 0000-0001-7335-4131
Ching-Feng HuangCollege of Medicine, Tzu Chi University, Hualien 970, Taiwan.
Ming-Nan LinCollege of Medicine, Tzu Chi University, Hualien 970, Taiwan.
Chiao-Erh ChangInstitute of Epidemiology and Preventive Medication, College of Public Health, National Taiwan University, Taipei 106, Taiwan.ORCID 0000-0003-3361-5039
Chia-Chen ChangCollege of Medicine, Tzu Chi University, Hualien 970, Taiwan.
Chin-Lon LinCollege of Medicine, Tzu Chi University, Hualien 970, Taiwan.ORCID 0000-0003-1805-8502

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The number of people living with dementia globally is increasing rapidly, and there is no effective therapy. Dietary pattern is one important risk factor for the development and progression of dementia. We undertake this study to determine whether Taiwanese vegetarian diet in midlife affects dementia incidence in later years in a prospective cohort. We followed 5710 participants (average age less than 60) in the Tzu Chi Vegetarian Study (TCVS). We started recruiting in 2005 and followed until the end of 2014 when the database changed from ICD-9-CM to ICD-10-CM codes. The incidence of dementia was obtained through linkage to the National Health Insurance Research Database. We used Cox proportional hazards regression to estimate the hazard ratio of dementia between vegetarians and nonvegetarians. There were 121 cases of dementia (37 vegetarians and 84 nonvegetarians) diagnosed. Vegetarians were associated with reduced risk of clinically overt dementia compared with nonvegetarians (hazard ratio = 0.671, confidence interval: 0.452−0.996, p < 0.05) after adjusting for gender, age, smoking, drinking, education level, marriage, regular exercise, and comorbidities with stepwise regression.

Indexed as

DementiaVegetariansCohort StudiesHumansProspective StudiesRisk FactorsAlzheimer’s diseasecardiometabolic risk factorsdementia incidencevegetarian diet

Identifiers

PMID35276947
PMCPMC8839073

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.