Evidence map›Paper›PMID 35276919›Full record

SynthesisNutrients2022

The Effect of Nutrition on Aging-A Systematic Review Focusing on Aging-Related Biomarkers.

Catarina Leitão, Anna Mignano, Marta Estrela, Margarida Fardilha, Adolfo Figueiras, Fátima Roque, Maria Teresa Herdeiro

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 2 pooled it
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. A Short Questionnaire for Evaluating Mediterranean Diet Adherence and Nutritional Sustainability: Validation in Turkish Adults.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Dietary habits and successful aging in Chinese older adults: a cross-sectional analysis of the CLHLS.Archives of public health = Archives belges de sante publique · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Catarina LeitãoInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-1262-0453
Anna MignanoInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0001-5365-7186
Marta EstrelaInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0001-6123-3818
Margarida FardilhaInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0001-7459-9173
Adolfo FigueirasConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), 28001 Madrid, Spain.ORCID 0000-0002-5766-8672
Fátima RoqueResearch Unit for Inland Development, Polytechnic of Guarda (UDI-IPG), 6300-559 Guarda, Portugal.ORCID 0000-0003-0169-3788
Maria Teresa HerdeiroInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-0500-4049
University of Aveiro · PTInstituto de Investigación Sanitaria de Santiago · ESUniversity of Beira Interior · PT

Funding

Fundação para a Ciência e Tecnologia FCT (UI/DB/151352/2021)Fundação para a Ciência e Tecnologia iBiMED (UIDB/04501/2020)
6 · The paper itself

Abstract

Despite the increasing life expectancy, an individual's later years tends to be accompanied by a decrease in the quality of life. Though biological changes that occur through the natural process of aging cannot be controlled, the risk factors associated with lifestyle can. Thus, the main goal of this systematic review was to evaluate how nutrition can modulate aging. For this purpose, thirty-six studies were selected on (i) the efficiency of nutrition's effect on aging, (ii) the evaluation of biomarkers that promote healthy aging, and (iii) how to increase longevity through nutrition, and their quality was assessed. The results showed that choosing low carbohydrate diets or diets rich in vegetables, fruits, nuts, cereals, fish, and unsaturated fats, containing antioxidants, potassium, and omega-3 decreased cardiovascular diseases and obesity risk, protected the brain from aging, reduced the risk of telomere shortening, and promoted an overall healthier life. With this study, the conclusion is that since the biological processes of aging cannot be controlled, changing one's nutritional patterns is crucial to prevent the emergence and development of diseases, boost longevity, and, mostly, to enhance one's quality of life and promote healthy aging.

Indexed as

Nutritional StatusQuality of LifeAgingAnimalsBiomarkersLongevityBiomarkersbiomarkerscardiovascular disease riskhealthy agingnutrition

Identifiers

PMID35276919
PMCPMC8838212
OpenAlexW4210318715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.