Evidence map›Paper›PMID 35276917›Full record

ReviewNutrients2022

A Natural Plant Source-Tea Polyphenols, a Potential Drug for Improving Immunity and Combating Virus.

Mengyu Hong, Lu Cheng, Yanan Liu, Zufang Wu, Peng Zhang, Xin Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Antioxidants (Basel, Switzerland) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mengyu HongDepartment of Food Science and Engineering, Ningbo University, Ningbo 315211, China.
Lu ChengDepartment of Food Science, Rutgers University, New Brunswick, NJ 08901, USA.ORCID 0000-0003-4188-3535
Yanan LiuDepartment of Food Science and Engineering, Ningbo University, Ningbo 315211, China.
Zufang WuDepartment of Food Science and Engineering, Ningbo University, Ningbo 315211, China.
Peng ZhangDepartment of Student Affairs, Xinyang Normal University, Xinyang 464000, China.
Xin ZhangDepartment of Food Science and Engineering, Ningbo University, Ningbo 315211, China.ORCID 0000-0002-5795-9197
Ningbo University · CNRutgers, The State University of New Jersey · USXinyang Normal University · CN

Funding

the Ningbo Natural Science Foundation 2021J107Zhejiang Provincial Key Research and Development Program 2020C02037
6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) is still in a global epidemic, which has profoundly affected people's lives. Tea polyphenols (TP) has been reported to enhance the immunity of the body to COVID-19 and other viral infectious diseases. The inhibitory effect of TP on COVID-19 may be achieved through a series of mechanisms, including the inhibition of multiple viral targets, the blocking of cellular receptors, and the activation of transcription factors. Emerging evidence shows gastrointestinal tract is closely related to respiratory tract, therefore, the relationship between the state of the gut-lung axis microflora and immune homeostasis of the host needs further research. This article summarized that TP can improve the disorder of flora, reduce the occurrence of cytokine storm, improve immunity, and prevent COVID-19 infection. TP may be regarded as a potential and valuable source for the design of new antiviral drugs with high efficiency and low toxicity.

Indexed as

COVID-19 Drug TreatmentGastrointestinal MicrobiomeHumansPolyphenolsSARS-CoV-2TeaPolyphenolsTeaantiviral effectCOVID-19gut-lung axisimmunitytea polyphenols

Identifiers

PMID35276917
PMCPMC8839699
OpenAlexW4210260273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.