Evidence map›Paper›PMID 35276915›Full record

ArticleNutrients2022

Elovl2-Ablation Leads to Mitochondrial Membrane Fatty Acid Remodeling and Reduced Efficiency in Mouse Liver Mitochondria.

Alexia Gómez Rodríguez, Emanuela Talamonti, Alba Naudi, Anastasia V Kalinovich, Anna M Pauter, Gustavo Barja, Tore Bengtsson, Anders Jacobsson, Reinald Pamplona, Irina G Shabalina

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. The role of fatty acid metabolism on B cells and B cell-related autoimmune diseases.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Alexia Gómez RodríguezDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-10691 Stockholm, Sweden.
Emanuela TalamontiDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-10691 Stockholm, Sweden.ORCID 0000-0002-5769-9022
Alba NaudiDepartment of Experimental Medicine, Biomedical Research Institute of Lleida (UdL-IRBLleida), University of Lleida, E-25198 Lleida, Spain.
Anastasia V KalinovichDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-10691 Stockholm, Sweden.
Anna M PauterDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-10691 Stockholm, Sweden.
Gustavo BarjaDepartment of Animal Physiology II, Faculty of Biological Sciences, Complutense University, E-28040 Madrid, Spain.ORCID 0000-0001-5736-4735
Tore BengtssonDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-10691 Stockholm, Sweden.
Anders JacobssonDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-10691 Stockholm, Sweden.
Reinald PamplonaDepartment of Experimental Medicine, Biomedical Research Institute of Lleida (UdL-IRBLleida), University of Lleida, E-25198 Lleida, Spain.ORCID 0000-0003-4337-6107
Irina G ShabalinaDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-10691 Stockholm, Sweden.ORCID 0000-0002-2915-6450
Stockholm University · SEUniversidad Complutense de Madrid · ESUniversitat de Lleida · ES

Funding

FEDER funds from the European Union ("A way to build Europe") FEDER funds from the European Union ("A way to build Europe")Generalitat of Catalonia: Agency for Management of University and Research Grants 2017SGR696Spanish Ministry of Science, Innovation, and Universities RTI2018-099200-B-I00Swedish Science Council VR-MT 2019-01508Swedish Science Council VR-NT 2017-04715
6 · The paper itself

Abstract

The fatty acid elongase elongation of very long-chain fatty acids protein 2 (ELOVL2) controls the elongation of polyunsaturated fatty acids (PUFA) producing precursors for omega-3, docosahexaenoic acid (DHA), and omega-6, docosapentaenoic acid (DPA

Indexed as

Mitochondria, LiverMitochondrial MembranesAnimalsFatty AcidsLiverMiceMitochondriaFatty Acidsadenine nucleotide translocasedocosahexaenoic acid (DHA) deficiencymembrane permeabilizationmitochondrial functionoxidative damage markerspolyunsaturated fatty acids

Identifiers

PMID35276915
PMCPMC8838343
OpenAlexW4221024989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.