ArticleNutrients2022
Genetically Predicted Circulating Copper and Risk of Chronic Kidney Disease: A Mendelian Randomization Study.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- Bibliometrics and visualization analysis: Big data research on diabetic kidney disease from 2000 to 2025.Medicine · 2026Article
- Review
- The effect of micronutrient levels on leukocyte telomere length: A Mendelian randomization study.Medicine · 2026Article
- Copper-instigated modulatory cell mortality mechanisms and progress in kidney diseases.Renal failure · 2025Review
- Article
- Article
- Association between copper exposure and renal fibrosis in patients with chronic kidney disease: evidence from Mendelian randomization and a retrospective study.Frontiers in public health · 2025Article
- The relationship between copper intake and chronic kidney disease/diabetic kidney disease: insights from NHANES data (2011-2018).Frontiers in endocrinology · 2025Article
- Recent advances in the application of Mendelian randomization to chronic kidney disease.Renal failure · 2024Review
- Safety and impact of the Mediterranean diet in patients with chronic kidney disease: a pilot randomized crossover trial.Frontiers in nutrition · 2024Article
- Article
- The Combined Administration of Vitamin C and Copper Induces a Systemic Oxidative Stress and Kidney Injury.Biomolecules · 2023Article
- Urinary Copper Excretion Is Associated with Long-Term Graft Failure in Kidney Transplant Recipients.American journal of nephrology · 2023Article
- Potential Role of Copper in Diabetes and Diabetic Kidney Disease.Metabolites · 2022Review
- Benefits and risks of essential trace elements in chronic kidney disease: a narrative review.Annals of translational medicine · 2022Review
- Effect of Copper on the Function of Isolated Porcine Kidneys Stored Using Simple Hypothermia.International journal of molecular sciences · 2022Article
- An Overview of Methods and Exemplars of the Use of Mendelian Randomisation in Nutritional Research.Nutrients · 2022Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Elevated circulating copper levels have been associated with chronic kidney disease (CKD), kidney damage, and decline in kidney function. Using a two sample Mendelian randomization approach where copper-associated genetic variants were used as instrumental variables, genetically predicted higher circulating copper levels were associated with higher CKD prevalence (odds ratio 1.17; 95% confidence interval 1.04, 1.32;
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.