Evidence map›Paper›PMID 35276864›Full record

ArticleNutrients2022

Carvacrol Suppresses Inflammatory Biomarkers Production by Lipoteichoic Acid- and Peptidoglycan-Stimulated Human Tonsil Epithelial Cells.

Niluni M Wijesundara, Song F Lee, Ross Davidson, Zhenyu Cheng, H P Vasantha Rupasinghe

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Comparative Effects of Flurbiprofen and Benzydamine on COX-2/PGEInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. MRGPRX2 Mediates Mast Cell-Induced Endometriosis Pain Through the Sensitization of Sensory Neurons via Histamine/HRH1/TRPV1 Signaling Pathway.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  4. Natural products in the treatment of diabetic foot infection.European journal of medical research · 2025
    Review
  5. Article
  6. Oregano Essential Oil in Livestock and Veterinary Medicine.Animals : an open access journal from MDPI · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. Effect ofNutrients · 2023
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Niluni M WijesundaraDepartment of Biology, Faculty of Science, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Song F LeeDepartment of Microbiology & Immunology, Dalhousie University, Halifax, NS B3H 6R8, Canada.
Ross DavidsonDepartment of Microbiology & Immunology, Dalhousie University, Halifax, NS B3H 6R8, Canada.
Zhenyu ChengDepartment of Microbiology & Immunology, Dalhousie University, Halifax, NS B3H 6R8, Canada.ORCID 0000-0002-7240-9126
H P Vasantha RupasingheDepartment of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, NS B2N 5E3, Canada.ORCID 0000-0003-3435-0052
Dalhousie University · CA

Funding

Natural Sciences and Engineering Research Council CRDPJ 448052
6 · The paper itself

Abstract

Pharyngitis is an inflammation of the pharynx caused by viral, bacterial, or non-infectious factors. In the present study, the anti-inflammatory efficacy of carvacrol was assessed using an in vitro model of streptococcal pharyngitis using human tonsil epithelial cells (HTonEpiCs) induced with

Indexed as

Palatine TonsilPeptidoglycanBiomarkersCell WallCymenesEpithelial CellsHumansLipopolysaccharidesTeichoic AcidsBiomarkerscarvacrolCymenesLipopolysaccharideslipoteichoic acidPeptidoglycanTeichoic Acidsanti-inflammatorycarvacrolcytokinesinflammationLTAPGNstreptococcal pharyngitisStreptococcus pyogenes

Identifiers

PMID35276864
PMCPMC8840435
OpenAlexW4210333912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.