Evidence map›Paper›PMID 35276830›Full record

ArticleNutrients2022

Association of Food Allergy, Respiratory Allergy, and Skin Allergy with Attention Deficit/Hyperactivity Disorder among Children.

Guifeng Xu, Buyun Liu, Wenhan Yang, Linda G Snetselaar, Mingwu Chen, Wei Bao, Lane Strathearn

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

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  15. Fungal Aeroallergens-The Impact of Climate Change.Journal of fungi (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Guifeng XuDepartment of Pediatrics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China.
Buyun LiuDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.ORCID 0000-0002-9553-8764
Wenhan YangDepartment of Nutrition and Food Hygiene, School of Public Health, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Linda G SnetselaarDepartment of Epidemiology, University of Iowa, Iowa City, IA 52242, USA.
Mingwu ChenDepartment of Pediatrics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China.ORCID 0000-0001-8760-949X
Wei BaoDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Lane StrathearnCenter for Disabilities and Development, University of Iowa Stead Family Children's Hospital, Iowa City, IA 52242, USA.ORCID 0000-0001-5870-8843
University of Science and Technology of China · CNUniversity of Iowa · USGuangdong Pharmaceutical University · CN

Funding

University of Iowa Hawkeye Intellectual and Developmental Disabilities Research Center (Hawk-IDDRC)P50HD103556 · NICHD · UNIVERSITY OF IOWA · PI EDWIN TED G. ABEL, Lane Strathearn · 2021 to 2026
$8.5M
6 · The paper itself

Abstract

backgroundPrevious studies have predominately examined associations of respiratory allergy and skin allergy with ADHD, but little is known about the association between food allergy and ADHD.

methodsWe included 192,573 children aged 4-17 years from the National Health Interview Survey (NHIS), a leading health survey in a nationally representative sample of the US population. Allergy conditions and ADHD were defined based on an affirmative response in the NHIS questionnaire. We used weighted logistic regression to estimate the odds ratio (OR) of ADHD.

resultsAmong the 192,573 children, 15,376 reported ADHD diagnosis. The prevalence of ADHD was higher among children with allergic conditions: 12.66% vs. 7.99% among children with and without food allergy; 12.16% vs. 7.63% among children with and without respiratory allergy; and 11.46% vs. 7.83% among children with and without skin allergy. After adjusting for covariates, the OR of ADHD was 1.72 (95% CI, 1.55-1.91) comparing children with and without food allergy, 1.50 (95% CI, 1.41-1.59) comparing children with and without respiratory allergy, and 1.65 (95% CI, 1.55-1.75) comparing children with and without skin allergy. The observed associations remained significant after mutual adjustment for other allergic conditions.

conclusionsIn a nationally representative sample of US children, we found a significant association of common allergic conditions (food allergy, respiratory allergy, and skin allergy) with ADHD.

Indexed as

Attention Deficit Disorder with HyperactivityDermatitis, AtopicFood HypersensitivityAdolescentChildChild, PreschoolCross-Sectional StudiesHumansPrevalenceattention deficit/hyperactivity disorderfood allergyrespiratory allergyskin allergy

Identifiers

PMID35276830
PMCPMC8838767
OpenAlexW4207002634

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.