Evidence map›Paper›PMID 35276794›Full record

ArticleNutrients2022

Glucoraphanin Increases Intracellular Hydrogen Sulfide (H

Laura Gambari, Marli Barone, Emanuela Amore, Brunella Grigolo, Giuseppe Filardo, Renato Iori, Valentina Citi, Vincenzo Calderone, Francesco Grassi

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Nutraceutical potential of radish (Food chemistry: X · 2026
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  8. Beneficial Effect of HInternational journal of molecular sciences · 2022
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Laura GambariLaboratorio RAMSES, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.ORCID 0000-0001-8126-5040
Marli BaroneLaboratorio RAMSES, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.
Emanuela AmoreLaboratorio RAMSES, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.
Brunella GrigoloLaboratorio RAMSES, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.ORCID 0000-0002-3990-6745
Giuseppe FilardoApplied and Translational Research Center (ATRc), IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.
Renato IoriResearch and Innovation Centre, Department of Food Quality and Nutrition, Fondazione Edmund Mach, 38098 San Michele all'Adige, Italy.
Valentina CitiDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Vincenzo CalderoneDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Francesco GrassiLaboratorio RAMSES, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.ORCID 0000-0002-5127-9561
Istituto Ortopedico Rizzoli · ITUniversity of Pisa · ITFondazione Edmund Mach · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteopenia and osteoporosis are among the most prevalent consequences of ageing, urging the promotion of healthy nutritional habits as a tool in preventing bone fractures. Glucosinolates (GLSs) are organosulfur compounds considered relatively inert precursors of reactive derivatives isothiocyanates (ITCs). Recent evidence suggests that GLSs may exert biological properties based on their capacity to release hydrogen sulfide (H

Indexed as

Hydrogen SulfideMesenchymal Stem CellsCells, CulturedGlucosinolatesHumansOsteogenesisOximesSulfoxidesglucoraphaninGlucosinolatesHydrogen SulfideOximesSulfoxidesglucoraphaninhydrogen sulfidemesenchymal stromal cellsnutritional supplementsosteoblastosteoporosis

Identifiers

PMID35276794
PMCPMC8837953
OpenAlexW4206800325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.