ReviewNutrients2022
Traditional and Medical Applications of Fasting.
Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 52 citations in OpenAlex.
- Stage-Specific Dynamic of Gut Microbiota Across the Musk-Secretion Cycle in Forest Musk Deer (Microorganisms · 2026Article
- The Effects of Fasting and Caloric Restriction on Reproductive Hormones: A Systematic Review, Meta-Analysis, and GRADE Assessment.Food science & nutrition · 2026Review
- Remodelling of the gut virome after long-term fasting.NPJ biofilms and microbiomes · 2026Article
- Modelling 16/8 intermittent fasting and breakfast-skipping in mouse adipocytes 3T3-L1 in vitro: a transcriptomics study.Journal, genetic engineering & biotechnology · 2026Article
- Gastrointestinal symptoms and eating patterns during Ramadan fasting among university students in Palestine: a cross-sectional study.BMC public health · 2026Article
- Marked Increases in Continuous Glucose Monitor-Detected Hypoglycemia During a Seven-Day Water-Only Fast in Healthy Men and Women.Journal of diabetes science and technology · 2026Article
- Time-Restricted Eating, Cardiometabolic Health in Obesity and The Optimal Length of the Eating Window.Current nutrition reports · 2026Review
- Culturally Informed Dietary Approaches for Cardiometabolic Risk Reduction in South Asians: An Evidence-Based Review.Journal of clinical medicine · 2026Review
- Ramadan intermittent fasting and the gut microbiome: modulation of diversity and implications for metabolic health.Frontiers in nutrition · 2026Review
- Intermittent and periodic fasting: molecular mechanisms, health benefits and research challenges.Frontiers in nutrition · 2026Review
- The Role of Religiosity on Racial/Ethnic Disparities in Non-adherence to Antihypertensive Medications.Journal of racial and ethnic health disparities · 2025Article
- Review
- Perspectives of older adults with memory decline participating in a prolonged nightly fasting (PNF) pilot study: A qualitative exploration.Journal of clinical and translational science · 2025Article
- Intermittent fasting in the treatment of type 2 diabetes.Frontiers in nutrition · 2025Review
- Impact of intermittent fasting on physical activity: a national survey of Chinese residents aged 18-80 years.Frontiers in physiology · 2025Article
- Nourishing the evidence: exposing bias and filling gaps in isocaloric intermittent fasting research-An opinion.Frontiers in nutrition · 2025Article
- Ramadan fasting model modulates biomarkers of longevity and metabolism in male obese and non-obese rats.Scientific reports · 2024Article
- Intermittent Fasting: Myths, Fakes and Truth on This Dietary Regimen Approach.Foods (Basel, Switzerland) · 2024Review
- Investigation of the effect of Ramadan fasting on serum levels of melatonin, cortisol, and serotonin: the case of Turkey.Irish journal of medical science · 2024Article
- Complementary and alternative medicine use in migraine patients: results from a national patient e-survey.Frontiers in neurology · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fasting has been practiced for millennia, for religious, ethical, or health reasons. It is also commonplace among different species, from humans, to animals, to lower eukaryotes. Research on fasting is gaining traction based on recent studies that show its role in many adaptive cellular responses such as the reduction of oxidative damage and inflammation, increase of energy metabolism, and in boosting cellular protection. In this expert review, we recount the historical evolution of fasting and we critically analyze its current medical applications, including benefits and caveats. Based on the available data, we conclude that the manipulation of dietary intake, in the form of calorie restriction, intermittent fasting, dietary restriction with the exclusion of some nutrients, prolonged fasting, and so forth, is anthropologically engraved in human culture possibly because of its positive health effects. Indeed, many studies show that fasting ameliorates many biochemical parameters related to cardiovascular and cancer risk, and neurodegeneration. Mechanistic studies are plentiful, but largely limited to cell cultures or laboratory animals. Understandably, there are no controlled trials of any form of fasting that gauge the effects on [any cause] mortality. Physicians should be aware that misinformation is pervasive and that their patients often adopt dietary regimens that are far from being clinically validated. Moreover, doctors are often unaware of their patients' religious or traditional fasting and of its potential health effects. Based on current evidence, no long-term fasting should be undertaken without medical supervision until future research will hopefully help shed further light on fasting and its effects on human health.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.