Evidence map›Paper›PMID 35276789›Full record

Trial reportNutrients2022

Feasibility and Acceptability of a Dietary Intervention to Reduce Salt Intake and Increase High-Nitrate Vegetable Consumption in Malaysian Middle-Aged and Older Adults with Elevated Blood Pressure: Findings from the DePEC-Nutrition Trial.

Siew Siew Lee, Andrea McGrattan, Yee Chang Soh, Mawada Alawad, Tin Tin Su, Uma Devi Palanisamy, Azizah Mat Hussin, Zaid Bin Kassim, Ahmad Nizal Bin Mohd Ghazali, Blossom Christa Maree Stephan and 5 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Siew Siew LeeGlobal Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.
Andrea McGrattanSchool of Biomedical, Nutritional and Sports Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.ORCID 0000-0003-1521-213X
Yee Chang SohGlobal Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.ORCID 0000-0002-2254-811X
Mawada AlawadGlobal Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.
Tin Tin SuGlobal Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.ORCID 0000-0003-0387-6406
Uma Devi PalanisamyJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.ORCID 0000-0002-8615-8241
Azizah Mat HussinInstitute of Medical Science Technology, Universiti Kuala Lumpur, Kajang 43000, Malaysia.
Zaid Bin KassimDistrict Health Office, Pejabat Kesihatan Daerah (PKD) Segamat, Segamat 85000, Malaysia.
Ahmad Nizal Bin Mohd GhazaliDistrict Health Office, Pejabat Kesihatan Daerah (PKD) Segamat, Segamat 85000, Malaysia.
Blossom Christa Maree StephanInstitute of Mental Health, School of Medicine, University of Nottingham, Nottingham NG7 2TU, UK.
Pascale AlloteyInternational Institute for Global Health, United Nations University, Kuala Lumpur 56000, Malaysia.
Daniel D ReidpathSouth East Asia Community Observatory (SEACO), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 45700, Malaysia.
Louise RobinsonPopulation Health Science Institute, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
Devi MohanGlobal Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.ORCID 0000-0002-0898-2729
Mario SiervoSchool of Life Sciences, University of Nottingham Medical School, Nottingham NG7 2UH, UK.
Monash University Malaysia · MYNewcastle University · GBUniversity of Nottingham · GBUnited Nations University-International Institute for Global Health · MYUniversity of Kuala Lumpur · MY

Funding

National Institute for Health Research GHR Group: 16/137/62 NIHR Global Health Research Group on Dementia Prevention and En-hanced Care (DePEC)
6 · The paper itself

Abstract

The DePEC-Nutrition trial is a complex dietary and behavioural intervention of salt intake reduction combined with increased high-nitrate vegetable consumption among Malaysian middle-aged and older adults with elevated blood pressure. This study aimed to assess the feasibility and acceptability of the trial. Participants were recruited from the South East Asia Community Observatory (SEACO) database and randomised into one of four groups: (1) low salt; (2) high-nitrate vegetable; (3) combined high-nitrate vegetable and low salt; and (4) control. The intervention included a combination of group counselling sessions, information booklets, reinforcement videos and text messages to modify dietary behaviour. The primary outcomes evaluated were the measures of feasibility and acceptability of (1) recruitment, follow-up attendance and retention; (2) data collection procedures and clinical outcome measures; and (3) individual and combined multi-modal dietary interventions. A total of 74 participants were recruited, and the 10-month retention rate was 73%. Data collection procedures were acceptable with minimal missing data. All intervention strategies were feasible and acceptable, with group counselling being the most acceptable strategy. This study provides important insights into improving the screening process of participants, facilitating their access to the research facilities and refining the measurement protocols and dietary recommendations, which are instrumental in formulating the design of a full-scale definitive DePEC-Nutrition trial.

Indexed as

NitratesVegetablesAgedBlood PressureFeasibility StudiesHumansMiddle AgedSodium Chloride, DietaryNitratesSodium Chloride, Dietarydementiadietary nitratefeasibility trialrandomised controlled trialreduced salt

Identifiers

PMID35276789
PMCPMC8839221
OpenAlexW4205803573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.