Evidence map›Paper›PMID 35276039›Full record

ArticleACS synthetic biology2022

Quantification of Microbial Robustness in Yeast.

Cecilia Trivellin, Lisbeth Olsson, Peter Rugbjerg

Abstract read
In one paragraph

Article in ACS synthetic biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Robustness of theBioengineering (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cecilia TrivellinDepartment of Biology and Biological Engineering, Division of Industrial Biotechnology, Chalmers University of Technology, Gothenburg 412 96, Sweden.
Lisbeth OlssonDepartment of Biology and Biological Engineering, Division of Industrial Biotechnology, Chalmers University of Technology, Gothenburg 412 96, Sweden.
Peter RugbjergDepartment of Biology and Biological Engineering, Division of Industrial Biotechnology, Chalmers University of Technology, Gothenburg 412 96, Sweden.ORCID 0000-0003-2561-5063

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stable cell performance in a fluctuating environment is essential for sustainable bioproduction and synthetic cell functionality; however, microbial robustness is rarely quantified. Here, we describe a high-throughput strategy for quantifying robustness of multiple cellular functions and strains in a perturbation space. We evaluated quantification theory on experimental data and concluded that the mean-normalized Fano factor allowed accurate, reliable, and standardized quantification. Our methodology applied to perturbations related to lignocellulosic bioethanol production showed that the industrial bioethanol producing strain

Indexed as

EthanolSaccharomyces cerevisiaeFermentationIndustrial MicrobiologyEthanolbioprocessFano factorhigh-throughputphenomicsrobustness quantificationyeast

Identifiers

PMID35276039
PMCPMC9016762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.