Evidence map›Paper›PMID 35276035›Full record

ArticleAnalytical chemistry2022

Leveraging Parameter Dependencies in High-Field Asymmetric Waveform Ion-Mobility Spectrometry and Size Exclusion Chromatography for Proteome-wide Cross-Linking Mass Spectrometry.

Ludwig R Sinn, Sven H Giese, Marchel Stuiver, Juri Rappsilber

Abstract read
In one paragraph

Article in Analytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Mapping amBio · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ludwig R SinnBioanalytics, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany.ORCID 0000-0003-4692-0681
Sven H GieseBioanalytics, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany.ORCID 0000-0002-9886-2447
Marchel StuiverBioanalytics, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany.
Juri RappsilberBioanalytics, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany.ORCID 0000-0001-5999-1310

Funding

Wellcome Trust 103139Wellcome Trust 103139/Z/13/ZWellcome Trust 203149
6 · The paper itself

Abstract

Ion-mobility spectrometry shows great promise to tackle analytically challenging research questions by adding another separation dimension to liquid chromatography-mass spectrometry. The understanding of how analyte properties influence ion mobility has increased through recent studies, but no clear rationale for the design of customized experimental settings has emerged. Here, we leverage machine learning to deepen our understanding of field asymmetric waveform ion-mobility spectrometry for the analysis of cross-linked peptides. Knowing that predominantly

Indexed as

Ion Mobility SpectrometryProteomeChromatography, GelChromatography, LiquidMass SpectrometryProteome

Identifiers

PMID35276035
PMCPMC8943524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.