SynthesisClinical infectious diseases : an official publication of the Infectious Diseases Society of America2022
Clinical Risk Factors Associated With Late-Onset Invasive Group B Streptococcal Disease: Systematic Review and Meta-Analyses.
Synthesis in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
- Gestational age modifies associations between Group B Streptococcus genomic characteristics and postnatal age at disease onset.Nature communications · 2026Article
- Type 2 diabetes mellitus exacerbates vaginal group BmSphere · 2026Article
- RodA promotes intestinal colonization by group BInfection and immunity · 2026Article
- Type 2 diabetes mellitus exacerbates vaginal group BbioRxiv : the preprint server for biology · 2026Article
- Current knowledge and future perspectives on management and prevention of group B streptococcus in neonates and young infants.Archives of disease in childhood. Fetal and neonatal edition · 2026Review
- Antibiotic treatment for neonatal sepsis: changing trends and future directions.Drugs in context · 2026Review
- Article
- A Comparison of Clinical, Neonatal, and Maternal Factors Between Early- and Late-Onset Group B Streptococcal Disease.Cureus · 2025Article
- An improved procedure based on fluorescence immunochromatography for rapid detection of group B streptococcus from enrichment cultures.BMC pregnancy and childbirth · 2025Article
- Global, regional, and national burden of meningitis among children, 1990-2021: An analysis of the global burden of disease study 2021.PloS one · 2025Article
- Breast milk-associated late-onset group B streptococcus sepsis in preterm triplets: A case report and literature review.Qatar medical journal · 2025Article
- A single-center investigation on serotypes, drug resistance and clinical significance of GBS isolates from pregnant and non-pregnant adults in Baoji, China.Frontiers in cellular and infection microbiology · 2025Article
- Role of the SaeRS Two-Component Regulatory System in Group BMicroorganisms · 2024Article
- The impact of butyrate on group BInfection and immunity · 2024Article
- Neonatal Group BSaudi medical journal · 2024Article
- Neonatal Group B Streptococcus Disease.Pediatrics in review · 2024Review
- Engagement of αFrontiers in microbiology · 2024Article
- Recurrent group B stretococcus infection in an extremely premature infant: as a preterm neonate, infant and toddler.BMJ case reports · 2023Article
- Pathogen- and Type-Specific Changes in Invasive Bacterial Disease Epidemiology during the First Year of the COVID-19 Pandemic in The Netherlands.Microorganisms · 2022Article
- Late-Onset Sepsis in a Premature Infant Mediated by Breast Milk: Mother-to-Infant Transmission of Group BInfection and drug resistance · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGroup B streptococcal (GBS) infection remains one of the most significant causes of late-onset sepsis and meningitis (LOGBS) among young infants. However, transmission routes and risk factors for LOGBS are not yet fully understood.
methodsWe conducted systematic reviews on clinical risk factors previously reported in the literature (prematurity, low birth weight [<2500 g], antenatal colonization, multiple-gestation pregnancy, maternal age <20 years, male infant sex, intrapartum fever, prolonged rupture of membranes) and meta-analyses to determine pooled estimates of risk.
resultsWe included 27 articles, reporting 5315 cases. Prematurity (odds ratio [OR] 5.66; 95% confidence interval [CI]: 4.43-7.22), low birth weight (OR 6.73; 95% CI: 4.68-9.67), maternal colonization (2.67; [2.07-3.45]), and multiple-gestation pregnancies (OR 8.01; 95% CI: 5.19-12.38) were associated with an increased risk of LOGBS.
conclusionsPrematurity/low birth weight and maternal colonization are major risk factors for LOGBS. Future GBS vaccine studies should try to establish the optimal time for vaccination during pregnancy to protect preterm infants.
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