Evidence map›Paper›PMID 35275724›Full record

ArticleScience advances2022

Bacterioboat-A novel tool to increase the half-life period of the orally administered drug.

Parmandeep Kaur, Sandip Ghosh, Arghya Bhowmick, Kundlik Gadhave, Satabdi Datta, Abhrajyoti Ghosh, Neha Garg, Roop L Mahajan, Biswarup Basu, Diptiman Choudhury

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Parmandeep KaurSchool of Chemistry and Biochemistry, Thapar Institute of Engineering and Technology, Patiala, Punjab, India.ORCID 0000-0003-1378-5356
Sandip GhoshDepartment of Neuroendocrinology and Experimental Hematology, Chittaranjan National Cancer Institute, Kolkata, West Bengal, India.ORCID 0000-0002-8265-9102
Arghya BhowmickDepartment of Biochemistry, Bose Institute, EN Block, Sector V, Bidhannagar, Kolkata, West Bengal 700091, India.
Kundlik GadhaveIndian Institute of Technology (IIT) Mandi, Mandi, Himachal Pradesh, India.ORCID 0000-0003-4530-4772
Satabdi DattaSchool of Chemistry and Biochemistry, Thapar Institute of Engineering and Technology, Patiala, Punjab, India.
Abhrajyoti GhoshDepartment of Biochemistry, Bose Institute, EN Block, Sector V, Bidhannagar, Kolkata, West Bengal 700091, India.ORCID 0000-0002-2469-3740
Neha GargIndian Institute of Technology (IIT) Mandi, Mandi, Himachal Pradesh, India.ORCID 0000-0003-2227-8292
Roop L MahajanThapar Institute of Engineering and Technology-Virginia Tech (USA) Centre for Excellence in Material Sciences; Thapar Institute of Engineering and Technology, Patiala, Punjab, India.ORCID 0000-0001-5647-0229
Biswarup BasuDepartment of Neuroendocrinology and Experimental Hematology, Chittaranjan National Cancer Institute, Kolkata, West Bengal, India.ORCID 0000-0002-5417-2735
Diptiman ChoudhurySchool of Chemistry and Biochemistry, Thapar Institute of Engineering and Technology, Patiala, Punjab, India.ORCID 0000-0003-1080-4558
Thapar Institute of Engineering & Technology · INBose Institute · INChittaranjan National Cancer Institute · INIndian Institute of Technology Mandi · INInstitute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The short half-life in the GI tract necessitates an excess of drugs causing side effects of oral formulations. Here, we report the development and deployment of Bacterioboat, which consists of surface-encapsulated mesoporous nanoparticles on metabolically active

Indexed as

Drug CarriersNanoparticlesAdministration, OralDrug Delivery SystemsHalf-LifeSolubilityDrug Carriers

Identifiers

PMID35275724
PMCPMC8916724
OpenAlexW4221115939

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.