ArticleJournal of Parkinson's disease2022
Patient-Related Factors Influencing Caregiver Burden in Parkinson's Disease Patients: Comparison of Effects Before and After Deep Brain Stimulation.
Article in Journal of Parkinson's disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Coping Behavior in Patients with Parkinson's Disease Prior to Subthalamic Deep Brain Stimulation and Association with Psychiatric Symptoms, Quality of Life and Neuropsychological Status.Movement disorders clinical practice · 2026Article
- Impact of X-linked dystonia-parkinsonism on caregiver strain, anxiety and depression.BMJ neurology open · 2026Article
- Progress and prospects of Parkinson's disease with depression research: A global bibliometric analysis based on CiteSpace.Medicine · 2025Article
- Caregiver Burden in Parkinson Disease: A Scoping Review of the Literature from 2017-2022.Journal of geriatric psychiatry and neurology · 2024Article
- Prevalence and Influencing Factors of Depression in Patients with Parkinson's Disease.Alpha psychiatry · 2023Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCaregivers of Parkinson's disease (PD) patients provide important support during the pre- and postoperative phase of deep brain stimulation (DBS). High levels of caregiver burden have been reported after DBS. However, a comparison between preoperative and postoperative burden and associated factors has been insufficiently studied.
objectiveTo investigate the influence of DBS on caregiver burden, and to identify the differential impact of patient-related factors on caregiver burden before and after DBS.
methodsConsecutive patients referred for DBS eligibility screening or during one-year follow-up assessments were included. Caregiver burden was measured with the short Zarit Burden Interview (ZBI-12). Inverse Probability Weighting (IPW) was used to compare caregiver burden between preoperative and postoperative assessments.
resultsWe included 47 patients (24 screening, 23 follow-up) (median age 65 years, 29.4% female sex). DBS did not impact caregiver burden (screening: median ZBI-12 9.5 (IQR 3.25, 16.75); follow-up median ZBI-12 6 (IQR 4, 14); IPW-coefficient 0.57 (95% CI -2.75, 3.89)). Worse caregiver burden during DBS screening was associated with worse patient-related scores on depressive symptoms, anxiety, QoL, and impulsiveness. Worse scores on depressive symptoms, anxiety, apathy, postural-instability-gait-disorder, and QoL were associated with worse caregiver burden at one-year follow-up.
conclusionDBS appears not associated with changes in caregiver burden. Various symptoms are valued differently between screening and follow-up assessments in terms of caregiver burden. Early recognition of caregivers "at risk" may improve guidance of patient-caregiver dyads throughout the DBS process.
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