Evidence map›Paper›PMID 35275374›Full record

ArticleAging clinical and experimental research2022

Prevalence and severity of cognitive dysfunction in patients referred for transcatheter aortic valve implantation (TAVI): clinical and cognitive impact at 1 year.

Charles Monnin, Matthieu Besutti, Fiona Ecarnot, Benoit Guillon, Marion Chatot, Romain Chopard, Mohamed Yahia, Nicolas Meneveau, François Schiele

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07193004 (Quality of Life Improvement After Transcatheter Aortic Valve Implantation), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07193004 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Quality of Life Improvement After Transcatheter Aortic Valve Implantation (TAVI) in the UK: A Prospective 1-Year Study (QualiTAVI-UK Trial)

Typeobservational_patient_registrySponsorUniversity Hospital Plymouth NHS TrustRan2025 to 2027Enrolled100ConditionsTAVI(Transcatheter Aortic Valve Implantation), TAVI, Quality of Life, Mental HealthArmsQuality of Life
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Charles MonninDepartment of Cardiology, University Hospital Besancon, 25000, Besancon, France.
Matthieu BesuttiDepartment of Cardiology, University Hospital Besancon, 25000, Besancon, France.
Fiona EcarnotDepartment of Cardiology, University Hospital Besancon, 25000, Besancon, France. Fiona.ecarnot@univ-fcomte.fr.ORCID http://orcid.org/0000-0002-4224-9731
Benoit GuillonDepartment of Cardiology, University Hospital Besancon, 25000, Besancon, France.
Marion ChatotDepartment of Cardiology, University Hospital Besancon, 25000, Besancon, France.
Romain ChopardDepartment of Cardiology, University Hospital Besancon, 25000, Besancon, France.
Mohamed YahiaDepartment of Cardiology, University Hospital Besancon, 25000, Besancon, France.
Nicolas MeneveauDepartment of Cardiology, University Hospital Besancon, 25000, Besancon, France.
François SchieleDepartment of Cardiology, University Hospital Besancon, 25000, Besancon, France.
Centre Hospitalier Universitaire de Besançon · FR

Funding

Edwards Lifesciences THV-I16-102/THV-I18-122
6 · The paper itself

Abstract

aimWe estimated the proportion and severity of cognitive disorders in an unselected population of patients referred for transcatheter aortic valve implantation (TAVI). Second, we describe clinical and cognitive outcomes at 1 year.

methodsEligible patients were aged ≥ 70 years, with symptomatic aortic stenosis and an indication for TAVI. The Montreal Cognitive Assessment (MoCA) was used to assess cognitive dysfunction (CD), defined as no CD if score ≥ 26, mild CD if 18-25; moderate CD if 10-18, and severe CD if < 10. We assessed survival and in-hospital complications at 6 months and 1 year.

resultsBetween June 2019 and October 2020, 105 patients were included; 21 (20%) did not undergo TAVI, and thus, 84 were analyzed; median age 85 years, 53.6% females, median EuroScore 11.5%. Median MoCA score was 22 (19-25); CD was excluded in 18 (21%), mild in 50 (59.5%), moderate in 15 (19%) and severe in 1. Mean MoCA score at follow-up was 21.9(± 4.69) and did not differ significantly from baseline (21.79 (± 4.61), p = 0.73). There was no difference in success rate, in-hospital complications, or death across CD categories.

conclusionThe clinical course of patients with mild or moderate CD is not different at 1 year after TAVI compared to those without cognitive dysfunction.

Indexed as

Aortic Valve StenosisCognitive DysfunctionHeart Valve Prosthesis ImplantationTranscatheter Aortic Valve ReplacementAged, 80 and overAortic ValveCognitionFemaleHumansMalePrevalenceRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeClock testCognitionCognitive impairmentGeriatricsMontreal Cognitive AssessmentTranscatheter aortic valve implantation

Identifiers

PMID35275374
OpenAlexW4220666470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.