ReviewCurrent treatment options in oncology2022
What Clinical Trials Are Needed for Treatment of Leiomyosarcoma?
Review in Current treatment options in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05548179 (An In Depth Study Investigating The Experiences of Patients In Leiomyosarcoma Clinical Trials), which is not on this map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An In Depth Study Investigating The Experiences of Patients In Leiomyosarcoma Clinical Trials
Who cites it
11 citing papers in PubMed, 10 citations in OpenAlex.
- Web-based nomograms for predicting overall survival and cancer-specific survival in retroperitoneal leiomyosarcoma: a population-based analysis.Journal of cancer research and clinical oncology · 2023Trial
- Clinical Heterogeneity and Survival Disparities in Leiomyosarcoma: An Exploratory Single-Center Retrospective Observational Study.Journal of clinical medicine · 2026Article
- Gene Expression Profiling ofJournal of clinical practice and research · 2026Article
- Metastatic Uterine Sarcomas: A Retrospective Analysis on Clinical Outcomes and Biology.Cureus · 2026Article
- Real-world comparison of doxorubicin-ifosfamide versus gemcitabine-docetaxel regimens in metastatic uterine leiomyosarcoma: a multicenter retrospective study.Discover oncology · 2025Article
- Leiomyosarcoma of lower urinary tract: Literature review.Central European journal of urology · 2025Review
- Urinary incontinence as the first clinical symptom of urinary bladder leiomyosarcoma.Central European journal of urology · 2025Article
- Surgical outcomes of patients with inferior vena cava leiomyosarcoma.Journal of vascular surgery. Venous and lymphatic disorders · 2024Article
- Establishment and characterization of NCC-LMS3-C1: a novel patient-derived cell line of leiomyosarcoma.Human cell · 2024Article
- Hyper-Dependence on NHEJ Enables Synergy between DNA-PK Inhibitors and Low-Dose Doxorubicin in Leiomyosarcoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023Article
- A case of pembrolizumab and lenvatinib as an alterntive therapy for leiomyosarcoma.Gynecologic oncology reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 8 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
opinion statementLeiomyosarcoma is one of the most common subtypes of soft tissue sarcomas accounting for approximately 20% of sarcomas. As leiomyosarcoma patients frequently develop metastatic disease, effective systemic therapies are needed to improve clinical outcomes. The overall activity of the currently available conventional systemic therapies and the prognosis of patients with advanced and/or metastatic disease are poor. As such, the treatment of this patient population remains challenging. As a result, there is a clear unmet medical need, and designing and performing meaningful clinical studies are of utmost importance to improve the prognosis of this patient group. Therefore, the aim of this review is to briefly summarize state-of-the-art treatments for leiomyosarcoma patients and to describe trial characteristics needed for informative clinical studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.