Evidence map›Paper›PMID 35275212›Full record

ArticleSocial cognitive and affective neuroscience2022

The OXTR rs53576 impacts moral permissibility of attempted but failed harms in populations of students and prisoners.

Linlin He, Jinting Liu, Yuhe Fan, Junhui Leng, Quanhe Wang, Cuimei Yang, Rui Zhang, Wenxuan Guo, Jieting Zhang, Pingyuan Gong

Open access · goldAbstract read
In one paragraph

Article in Social cognitive and affective neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. A transdisciplinary framework for empathy research.Frontiers in human neuroscience · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Linlin HeShaanxi Key Laboratory for Animal Conservation, Northwest University, Xi'an 710069, China.
Jinting LiuSchool of Psychology, Shenzhen University, Shenzhen 518060, China.
Yuhe FanCollege of Life Sciences, Northwest University, Xi'an 710069, China.
Junhui LengSchool of Psychology, Shenzhen University, Shenzhen 518060, China.
Quanhe WangCollege of Life Sciences, Northwest University, Xi'an 710069, China.
Cuimei YangSchool of Psychology, Shenzhen University, Shenzhen 518060, China.ORCID 0000-0003-2904-347X
Rui ZhangCollege of Life Sciences, Northwest University, Xi'an 710069, China.
Wenxuan GuoCollege of Life Sciences, Northwest University, Xi'an 710069, China.
Jieting ZhangSchool of Psychology, Shenzhen University, Shenzhen 518060, China.
Pingyuan GongShaanxi Key Laboratory for Animal Conservation, Northwest University, Xi'an 710069, China.ORCID 0000-0002-3915-2584
Northwest University · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous research has highlighted the roles of oxytocin in empathy and altruistic behaviors. Based on these findings, recent studies have examined the association between the oxytocin receptor gene (OXTR) and outcome-based moral judgment with sacrificial dilemmas (e.g. runaway trolley case). However, little is known about the relationships between OXTR polymorphisms and intent-based moral judgment of harms (e.g. attempted but failed harm or intentionally committed harm). This study investigated the association between the OXTR rs53576 and intent-based moral judgment in college students (N = 544) and prisoners (N = 540). Results indicated that both students and prisoners with the GG genotype of OXTR rs53576 rated attempted but failed harm as less permissible than those with the AA and AG genotypes. These findings highlight the role of the OXTR gene in intent-based moral judgment.

Indexed as

PrisonersReceptors, OxytocinGenotypeHumansMoralsOxytocinPolymorphism, Single NucleotideStudentsOXTR protein, humanOxytocinReceptors, Oxytocinaccidentally committed harmattempted but failed harmintentionally committed harmmoral judgmentoxytocin receptor gene

Identifiers

PMID35275212
PMCPMC9527464
OpenAlexW4213446164

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.