Evidence map›Paper›PMID 35274990›Full record

ArticleMolecular and cellular biology2022

An Evolutionarily Conserved AU-Rich Element in the 3' Untranslated Region of a Transcript Misannotated as a Long Noncoding RNA Regulates RNA Stability.

Emily A Dangelmaier, Xiao Ling Li, Corrine Corrina R Hartford, Julianna C King, Meira S Zibitt, Raj Chari, Ioannis Grammatikakis, Ashish Lal

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and cellular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Emily A Dangelmaier *Regulatory RNAs and Cancer Section, Genetics Branch, Center for Cancer Research (CCR), National Cancer Institutegrid.48336.3a (NCI), National Institutes of Health (NIH), Bethesda, Maryland, USA.
Xiao Ling Li *Regulatory RNAs and Cancer Section, Genetics Branch, Center for Cancer Research (CCR), National Cancer Institutegrid.48336.3a (NCI), National Institutes of Health (NIH), Bethesda, Maryland, USA.
Corrine Corrina R HartfordRegulatory RNAs and Cancer Section, Genetics Branch, Center for Cancer Research (CCR), National Cancer Institutegrid.48336.3a (NCI), National Institutes of Health (NIH), Bethesda, Maryland, USA.
Julianna C KingGenome Modification Core, Frederick National Lab for Cancer Research, National Cancer Institutegrid.48336.3a, Frederick, Maryland, USA.
Meira S ZibittRegulatory RNAs and Cancer Section, Genetics Branch, Center for Cancer Research (CCR), National Cancer Institutegrid.48336.3a (NCI), National Institutes of Health (NIH), Bethesda, Maryland, USA.
Raj ChariGenome Modification Core, Frederick National Lab for Cancer Research, National Cancer Institutegrid.48336.3a, Frederick, Maryland, USA.
Ioannis GrammatikakisRegulatory RNAs and Cancer Section, Genetics Branch, Center for Cancer Research (CCR), National Cancer Institutegrid.48336.3a (NCI), National Institutes of Health (NIH), Bethesda, Maryland, USA.
Ashish LalRegulatory RNAs and Cancer Section, Genetics Branch, Center for Cancer Research (CCR), National Cancer Institutegrid.48336.3a (NCI), National Institutes of Health (NIH), Bethesda, Maryland, USA.ORCID 0000-0002-4299-8177
National Institutes of Health · USFrederick National Laboratory for Cancer Research · US

Funding

Role of long non-coding RNAs in p53 signalingZIABC011646 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LAL, ASHISH · 2015 to 2025
$15.0M
6 · The paper itself

Abstract

One of the primary mechanisms of post-transcriptional gene regulation is the modulation of RNA stability. We recently discovered that

Indexed as

RNA, Long Noncoding3' Untranslated RegionsAU Rich ElementsGene Expression RegulationRNA Stability3' Untranslated RegionsRNA, Long Noncoding3’UTRAREAU-richconservedCRISPR/Cas9FORCPFOXA1LINC00675lincRNAlncRNAmicropeptidemiRNAmisannotatedmRNA decaymRNA stabilityNMDRNA stabilityTMEM238L

Identifiers

PMID35274990
PMCPMC9022526
OpenAlexW4220672896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.