Evidence map›Paper›PMID 35274811›Full record

ArticleCancer medicine2022

The efficacy of low-power cumulative high-intensity focused ultrasound treatment for recurrent desmoid tumor.

Xian Zhong, Xiaoye Hu, Peng Zhao, Yuebing Wang, Xue Feng Fang, Jiayi Shen, Hong Shen, Ying Yuan

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Local Treatment of Desmoid Tumors: An Update.Seminars in interventional radiology · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xian ZhongDepartment of Medical Oncology, Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.ORCID 0000-0001-5915-5531
Xiaoye HuDepartment of Medical Oncology, Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Peng ZhaoCollege of Metrology and Measurement Engineering, China Jiliang University, Hangzhou, China.
Yuebing WangCollege of Metrology and Measurement Engineering, China Jiliang University, Hangzhou, China.
Xue Feng FangDepartment of Medical Oncology, Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Jiayi ShenZhejiang University-University of Edinburgh (ZJU-UOE) Institute, Zhejiang University School of Medicine, Haining, China.ORCID 0000-0003-4157-7175
Hong ShenDepartment of Medical Oncology, Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Ying YuanDepartment of Medical Oncology, Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.ORCID 0000-0002-3922-9553
Zhejiang University · CNChina Jiliang University · CNZhejiang University-University of Edinburgh Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDesmoid tumors are rare neoplasms that are locally invasive. However, optimal treatment strategies for recurrent desmoid tumors remain controversial. High-intensity focused ultrasound (HIFU) has been reported as a noninvasive modality for treating recurrent desmoid tumors. However, its efficacy against massive desmoid tumors or those with complex anatomies remains unclear.

methodsWe developed a new therapeutic strategy called low-power cumulative HIFU and applied it to treat recurrent desmoid tumors.

resultsWe retrospectively collected data from 91 patients with recurrent desmoid tumors who underwent low-power cumulative HIFU treatment after surgical treatment failure. The mean ablation proportion of the HIFU treatment was 69.5%, and the objective response rate was 47.3%. The 5-year estimated progression-free survival rate for these patients was 69.3%.

conclusionLow-power cumulative HIFU treatment could achieve significant efficacy and long-term control of recurrent desmoid tumors.

Indexed as

Desmoid TumorsHigh-Intensity Focused Ultrasound AblationData CollectionHumansProgression-Free SurvivalRetrospective StudiesTreatment Outcomeaggressive fibromatosisdesmoid tumorefficacyhigh-intensity focused ultrasoundlow-power cumulative HIFU

Identifiers

PMID35274811
PMCPMC9119350
OpenAlexW4220786267

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.