ArticleANZ journal of surgery2022
Outpatient transperineal prostate biopsy under local anaesthesia is safe, well tolerated and feasible.
Article in ANZ journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06987071 (Efficacy Of Acupuncture in Pain and Anxiety During Transperineal Prostate Biopsy), which is not on this map. Cited by 15 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy Of Acupuncture in Pain and Anxiety During Transperineal Prostate Biopsy: A Prospective, Randomized, Sham-Controlled Trial
Who cites it
15 citing papers in PubMed.
- Effect of Video-Animated Information on Anxiety, Satisfaction, and Pain in Men Undergoing Transperineal Prostate Biopsy: A Randomized Controlled Study.Annals of surgical oncology · 2026Trial
- Infection risks and biopsy-associated complications in prostate cancer diagnosis: a review of recent literatures.Prostate cancer and prostatic diseases · 2026Review
- Transperineal cognitive versus trans-rectal fusion biopsy under local anesthesia: multicenter outcomes in detection rates, complications, and feasibility.International urology and nephrology · 2026Article
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- Safety of Single-Dose Oral Cefaclor Prophylaxis in Transperineal Prostate Biopsy.Research and reports in urology · 2026Article
- [Efficiency and safety of transperineal prostate biopsy with a single access point].Revista medica del Instituto Mexicano del Seguro Social · 2026Observational
- Evolution of the prostate cancer diagnostic paradigm: integrated evidence and clinical pathways from targeted biopsy to biopsy-free strategy.Frontiers in oncology · 2026Review
- Patient-reported outcome measures for pain and tolerability of transperineal prostate biopsy under local anaesthesia using the PrecisionPoint™ transperineal access system: A prospective study for a real-world patient experience.Investigative and clinical urology · 2025Article
- Targeted biopsy of the prostate.Abdominal radiology (New York) · 2025Review
- Evolution of anxiety management in prostate biopsy under local anesthesia: a narrative review.World journal of urology · 2024Review
- Investigation of the Effectiveness of Prostate Biopsy Density in Predicting Prostate Cancer Under Cognitive and Systematic Biopsy in Multi-Parametric Magnetic Resonance Imaging (mpMRI).Cancer management and research · 2024Article
- Patient-reported pain associated with grid-based transperineal magnetic resonance imaging (MRI)/ultrasound (US) software fusion biopsy of the prostate under local anesthesia: a multicenter experience.Translational andrology and urology · 2023Article
- Freehand transperineal prostate biopsy with a coaxial needle under local anesthesia: Experience from a single institution in Malaysia.Cancer pathogenesis and therapy · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundTransperineal biopsy (TPB) of the prostate has been increasingly utilized as it has reduced infection risks. Traditionally however, it is performed under general anaesthesia, thus it carries a differing set of risks. Recently, new studies have performed TPB under local anaesthesia with success. In the present study, we explored our experience of performing TPB under local anaesthesia in an Australian cohort.
methodsIn this prospective study based at a metropolitan outpatient clinic, patients were provided with TPB under local anaesthesia. We assessed prostate cancer detection rates, complication rates and patient tolerability. Pain tolerability was assess using patient reported pain score on the visual analogue scale. Follow up data was collected at days 7 and 30 post-biopsy via telephone interview.
resultsA total of 48 patients were enrolled in this study between June 2020 and March 2021. Median age was 65.5 years and median PSA was 6.95 ng/mL. Clinically significant prostate cancer was detected in 58% of patients. During the procedure, pain scores were rated the highest during infiltration of local anaesthetic agent with a median score of 5. By the conclusion of the procedure, median pain score was 1. Vast majority of patients (85.4%) would opt for a repeat TPB under local anaesthesia should the need for prostate biopsy arise again. Two of our patients experienced infectious complications, and one experienced urinary retention.
conclusionOur data is in line with currently available data and confirms that TPB under local anaesthesia can be achieved in a safe and tolerable manner.
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