Evidence map›Paper›PMID 35274279›Full record

Trial reportJournal of racial and ethnic health disparities2023

Symptoms and Comorbidities Differ Based on Race and Weight Status in Persons with HIV in the Northern United States: a Cross-Sectional Study.

Kierra R Butler, Faye R Harrell, Bridgett Rahim-Williams, Jeffrey M Robinson, Xuemin Zhang, Adwoa Gyamfi, Judith A Erlen, Wendy A Henderson

Registry-linked trialOpen access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Journal of racial and ethnic health disparities, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00222716 (Improving Adherence to Antiretroviral Therapy), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00222716 nacompletednot on this map

Improving Adherence to Antiretroviral Therapy

TypeinterventionalSponsorUniversity of PittsburghRan2004 to 2009Enrolled349ConditionsHIV InfectionsArmsProblem solving counseling
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Kierra R ButlerIndiana University School of Medicine, Indianapolis, IN, USA.
Faye R HarrellThe Catholic University of America, Washington, DC, USA.
Bridgett Rahim-WilliamsResearch Administration, Office of Research and Sponsored Programs, University of North Florida, Jacksonville, FL, USA.
Jeffrey M RobinsonUniversity of Maryland Baltimore County, Baltimore, MD, USA.
Xuemin ZhangOffice of the Director, National Institutes of Health, Bethesda, MD, USA.
Adwoa GyamfiSchool of Nursing, University of Connecticut, Storrs, CT, USA.
Judith A ErlenSchool of Nursing, University of Pittsburgh, Pittsburgh, PA, USA.
Wendy A HendersonSchool of Nursing, University of Connecticut, Storrs, CT, USA. wendy.henderson@uconn.edu.ORCID 0000-0003-3924-7118
University of Connecticut · USIndiana University School of MedicineNational Institutes of Health · USUniversity of America · USUniversity of Maryland, Baltimore County · USUniversity of North Florida · USUniversity of Pittsburgh · US

Funding

Symptom Distress Mechanisms in Digestive DisordersZIANR000018 · NINR · NATIONAL INSTITUTE OF NURSING RESEARCH · PI HENDERSON, WENDY · 2009 to 2019
$5.2M
Improving Adherence to Antiretroviral TherapyR01NR004749 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ERLEN, JUDITH A · 1998 to 2007
$3.6M
Exergame Physical Activity, Pain, and Functional Mobility Among Women with Knee OsteoarthritisK22MD006143 · NIMHD · BETHUNE-COOKMAN COLLEGE · PI RAHIM-WILLIAMS, BRIDGETT · 2015 to 2017
$710k
Intramural NIH HHS 1ZIANR000018Intramural NIH HHS ZIA NR000018NIH HHS 2R01NR04749NIMHD NIH HHS 1K22MD006143NIMHD NIH HHS K22 MD006143NINR NIH HHS R01 NR004749
6 · The paper itself

Abstract

backgroundPersons with HIV (PWHIV) on highly active antiretroviral treatments (HAART) may require specialized care based on health and demographic indicators. This study investigated the association of comorbidities, race, weight status, and gastrointestinal (GI) and cardiovascular (CV) symptoms among PWHIV.

methodsThe Symptom Checklist, Co-Morbidity Questionnaire, and Sociodemographic Questionnaire were used to assess weight status and GI and CV symptoms among 283 PWHIV. Data were analyzed using latent class analysis on John's Macintosh Project 13 Platform.

resultsParticipants were majority Black (50%), 69% male, and 35% AIDS diagnosed. Ages were 25 to 66. Clusters included least symptomatic status, weight gain, and weight loss by Black and non-Black participants. The non-Black weight gain cluster reported a higher incidence of AIDS (70.6% vs 38.2%), nausea (70.6% vs 17.6%), diarrhea (70.6% vs 26.5%), and shortness of breath (58.8% vs 20.6%) compared to the Black weight gain cluster. The Black weight loss cluster reported a higher incidence of CV symptoms such as chest palpitations (42.2% vs 2.7%), chest pain (44.4% vs 8.1%), and shortness of breath (73.3% vs 35.1%). Moreover, the Black weight loss cluster reported a higher incidence of all GI symptoms with the most prominent being diarrhea (71.1% vs 48.6%) compared to the non-Black weight loss cluster.

conclusionsThe existing racial disparities in health-related quality of life for PWHIV may be improved through precision health and nutrition modifications. Continued research is needed investigating differential health outcomes among PWHIV on HAART. CLINICAL TRIAL REGISTRATION NUMBER: NCT00222716. Registered 22 September 2005. Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT00222716?term=NCT00222716&draw=2&rank=1.

Indexed as

Acquired Immunodeficiency SyndromeHeart DiseasesHIV InfectionsAnti-Retroviral AgentsCross-Sectional StudiesFemaleHIVHumansMaleQuality of LifeUnited StatesAnti-Retroviral AgentsBMICardiovascularGastrointestinal symptomsHAARTHIVHypertension

Identifiers

PMID35274279
PMCPMC9988761
OpenAlexW4220892592

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.