Evidence map›Paper›PMID 35274118›Full record

ArticleLab on a chip2022

Establishment of physiologically relevant oxygen gradients in microfluidic organ chips.

Jennifer Grant, Elizabeth Lee, Micaela Almeida, Seongmin Kim, Nina LoGrande, Girija Goyal, Adama Marie Sesay, David T Breault, Rachelle Prantil-Baun, Donald E Ingber

Open access · greenAbstract read
In one paragraph

Article in Lab on a chip, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 63 citations in OpenAlex.

  1. AnmSystems · 2026
    Article
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  16. Microbial single-cell applications under anoxic conditions.Applied and environmental microbiology · 2024
    Review
  17. Intestinal organ chips for disease modelling and personalized medicine.Nature reviews. Gastroenterology & hepatology · 2024
    Review
  18. Review
  19. Review
  20. Organ-on-a-Chip:Pharmaceutics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jennifer GrantWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA. don.ingber@wyss.harvard.edu.
Elizabeth LeeWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA. don.ingber@wyss.harvard.edu.ORCID 0000-0001-5860-1739
Micaela AlmeidaWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA. don.ingber@wyss.harvard.edu.ORCID 0000-0002-1395-7130
Seongmin KimWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA. don.ingber@wyss.harvard.edu.
Nina LoGrandeWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA. don.ingber@wyss.harvard.edu.ORCID 0000-0003-1354-5336
Girija GoyalWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA. don.ingber@wyss.harvard.edu.
Adama Marie SesayWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA. don.ingber@wyss.harvard.edu.ORCID 0000-0003-0620-1076
David T BreaultDivision of Endocrinology, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0002-0402-4857
Rachelle Prantil-BaunWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA. don.ingber@wyss.harvard.edu.
Donald E IngberWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA. don.ingber@wyss.harvard.edu.ORCID 0000-0002-4319-6520
Harvard University · USBoston Children's Hospital · US

Funding

STRUCTURE-FUNCTION RELATIONSHIPS IN THE ALIMENTARY TRACTP30DK034854 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WAYNE I LENCER · 1986 to 2026
$32.4M
FDA HHSNIDDK NIH HHS P30 DK034854
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lab-On-A-Chip DevicesMicrofluidicsHumansIntestinal MucosaOxygenPorosityOxygen

Identifiers

PMID35274118
PMCPMC9088163
OpenAlexW4221135594

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.