Evidence map›Paper›PMID 35274012›Full record

ArticleFrontiers in cardiovascular medicine2022

Cardiac Alterations on 3T MRI in Young Adults With Sedentary Lifestyle-Related Risk Factors.

Gert J H Snel, Maaike van den Boomen, Katia Hurtado-Ortiz, Riemer H J A Slart, Vincent M van Deursen, Christopher T Nguyen, David E Sosnovik, Rudi A J O Dierckx, Birgitta K Velthuis, Ronald J H Borra and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Gert J H SnelDepartment of Radiology, Medical Imaging Center, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Maaike van den BoomenDepartment of Radiology, Medical Imaging Center, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Katia Hurtado-OrtizFaculty of Medicine, National Autonomous University of Mexico (UNAM), Ciudad Universitaria, Mexico City, Mexico.
Riemer H J A SlartDepartment of Nuclear Medicine and Molecular Imaging, Medical Imaging Center, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Vincent M van DeursenDepartment of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Christopher T NguyenDepartment of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
David E SosnovikDepartment of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Rudi A J O DierckxDepartment of Nuclear Medicine and Molecular Imaging, Medical Imaging Center, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Birgitta K VelthuisDepartment of Radiology, University Medical Center Utrecht, University of Utrecht, Utrecht, Netherlands.
Ronald J H BorraDepartment of Radiology, Medical Imaging Center, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Niek H J PrakkenDepartment of Radiology, Medical Imaging Center, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
University of Groningen · NLUniversity Medical Center Groningen · NLAthinoula A. Martinos Center for Biomedical Imaging · USHarvard University · USMassachusetts General Hospital · USUniversidad Nacional Autónoma de México · MXUtrecht University · NL

Funding

Serial evaluation of cardioprotective effects of exercise training in heart failure using cardiac diffusion tensor MRIR01HL151704 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NGUYEN, CHRISTOPHER T · 2020 to 2024
$3.4M
NHLBI NIH HHS R01 HL151704
6 · The paper itself

Abstract

Background: Young adult populations with the sedentary lifestyle-related risk factors overweight, hypertension, and type 2 diabetes (T2D) are growing, and associated cardiac alterations could overlap early findings in non-ischemic cardiomyopathy on cardiovascular MRI. We aimed to investigate cardiac morphology, function, and tissue characteristics for these cardiovascular risk factors. Methods: Non-athletic non-smoking asymptomatic adults aged 18-45 years were prospectively recruited and underwent 3Tesla cardiac MRI. Multivariate linear regression was performed to investigate independent associations of risk factor-related parameters with cardiac MRI values. Results: We included 311 adults (age, 32 ± 7 years; men, 49%). Of them, 220 subjects had one or multiple risk factors, while 91 subjects were free of risk factors. For overweight, increased body mass index (per SD = 5.3 kg/m Conclusions: Young asymptomatic adults with overweight, hypertension, and T2D show subclinical alterations in cardiac morphology, function, and tissue characteristics. These alterations should be considered in cardiac MRI-based clinical decision making.

Indexed as

cardiac functioncardiovascular magnetic resonance imaginghypertensionmyocardial tissue characterizationoverweighttype 2 diabetesyoung adults

Identifiers

PMID35274012
PMCPMC8902075
OpenAlexW4212999151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.