Evidence map›Paper›PMID 35273917›Full record

ArticleFrontiers in oncology2022

Circulating Tumor DNA Mutations in Progressive Gastrointestinal Stromal Tumors Identify Biomarkers of Treatment Resistance and Uncover Potential Therapeutic Strategies.

Tun Kiat Ko, Elizabeth Lee, Cedric Chuan-Young Ng, Valerie Shiwen Yang, Mohamad Farid, Bin Tean Teh, Jason Yongsheng Chan, Nagavalli Somasundaram

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Review
  6. Clinical Use of Liquid-Based Comprehensive Genomic Profiling in Gastrointestinal Stromal Tumors.Laboratory investigation; a journal of technical methods and pathology · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Angiogenesis in gastrointestinal stromal tumors: From bench to bedside.World journal of gastrointestinal oncology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tun Kiat KoLaboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, Singapore.
Elizabeth LeeLaboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, Singapore.
Cedric Chuan-Young NgLaboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, Singapore.
Valerie Shiwen YangDivision of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
Mohamad FaridDivision of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
Bin Tean TehLaboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, Singapore.
Jason Yongsheng ChanCancer Discovery Hub, National Cancer Centre Singapore, Singapore, Singapore.
Nagavalli SomasundaramDivision of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
National Cancer Centre Singapore · SGDuke-NUS Medical School · SGInstitute of Molecular and Cell Biology · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liquid biopsy circulating tumor DNA (ctDNA)-based approaches may represent a non-invasive means for molecular interrogation of gastrointestinal stromal tumors (GISTs). We deployed a customized 29-gene Archer

Indexed as

ctDNA (circulating tumor DNA)imatinibKITliquid biopsynon-invasive

Identifiers

PMID35273917
PMCPMC8904145
OpenAlexW4213351716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.