Evidence map›Paper›PMID 35273811›Full record

ArticleTranslational neuroscience2022

Relationship between subclasses low-density lipoprotein and carotid plaque.

Zhanhai Pan, Huiwen Guo, Qingqing Wang, Sha Tian, Xiaoxuan Zhang, Chengbo Li, Zheng Ma

Abstract read
In one paragraph

Article in Translational neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhanhai PanDepartment of Neurology, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, China.
Huiwen GuoDepartment of Neurology, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, China.
Qingqing WangDepartment of Neurology, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, China.
Sha TianDepartment of Neurology, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, China.
Xiaoxuan ZhangDepartment of Neurology, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, China.
Chengbo LiDepartment of Neurology, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, China.
Zheng MaDepartment of Neurology, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backgound: Low-density lipoprotein (LDL) cholesterol can lead to the occurrence of atherosclerotic plaques, but patients with normal LDL still have atherosclerotic plaques in clinical practice. With the proposal of LDL subclass, this experiment investigated the relationship between the LDL content of different subclasses and the stability of carotid plaques. Methods: Plaque stability was suggested by carotid ultrasound results. 37 patients with stable plaques were classified into one group and 41 patients with unstable plaques were classified into another group. The data of age, glycosylated hemoglobin (Ghb), and homocysteine (Hcy) were collected. The contents of LDL subclasses were measured by LIPOPRINT system. The data of total cholesterol (TC), LDL cholesterol, and triglyceride (TG) were collected. The plaque stability was assessed by carotid artery color Doppler ultrasound and the intima-media thickness (IMT) was measured. Results: The levels of LDL-1 subclass 19.00 (13.00, 27.50) and LDL-2 subclass (21.62 ± 7.24) in the stable plaque group were higher than those in the unstable plaque group ( Conclusion: Elevated LDL1 is associated with stable plaques whereas LDL3 was found associated with unstable plaques.

Indexed as

low-density lipoprotein subclassessmall-dense low-density lipoproteinunstable plaque

Identifiers

PMID35273811
PMCPMC8896331

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