Evidence map›Paper›PMID 35273735›Full record

ArticleAmerican journal of translational research2022

Treatment efficacy of Lianhua Qingwen capsules for eraly-stage COVID-19.

Si-Jia Fan, Jian-Kun Liao, Liu Wei, Bai-Yu Wang, Liu Kai, Du-Xun Tan

Abstract read
In one paragraph

Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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  6. The Potential of Ameliorating COVID-19 and Sequelae FromBioinformatics and biology insights · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Si-Jia FanDepartment of Emergency Intensive Care Unit, South China Hospital, Health Science Center, Shenzhen University Shenzhen 518116, Guangdong, China.
Jian-Kun LiaoDepartment of Emergency Intensive Care Unit, South China Hospital, Health Science Center, Shenzhen University Shenzhen 518116, Guangdong, China.
Liu WeiDepartment of Intensive Care Unit, SongGang People's Hospital Shenzhen 518105, Guangdong, China.
Bai-Yu WangDepartment of Anesthesiology, Jilin Cancer Hospital Changchun 130012, Jilin, China.
Liu KaiDepartment of Emergency Intensive Care Unit, South China Hospital, Health Science Center, Shenzhen University Shenzhen 518116, Guangdong, China.
Du-Xun TanDepartment of Emergency Intensive Care Unit, South China Hospital, Health Science Center, Shenzhen University Shenzhen 518116, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo systematically determine the effect of Lianhua Qingwen Capsules on the early antiviral and anti-inflammatory action against COVID-19 (Coronavirus 2019) and its applicational value in the treatment of COVID-19.

methodsThe clinical data of 66 early-mid-stage COVID-19 patients admitted to hospitals in Guangzhou between January 2020 and April 2020 were retrospectively analyzed. The patients receiving Lianhua Qingwen Capsule treatment were assigned to the observation group (n=33) and those given conventional therapy were included in the control group (n=33). The two groups were compared in terms of clinical effects and main symptom (fever, cough and fatigue) disappearance rate.

resultsIn comparison with the control group, 1) the total effective rate was significantly higher in the observation group (P<0.05); 2) the disappearance rates of fever, cough and fatigue were statistically higher in the observation group; 3) the treatment time was significantly shorter and patient recovery was significantly better in the observation group; 4) the laboratory index levels [white blood cell (WBC), interleukin-6 (IL-6), serum amyloid A (SAA)] were better in the observation group.

conclusionLianhua Qingwen Capsules can significantly improve the total effective rate for COVID-19 patients, as well as shorten the hospital stay and treatment time, which is worth of promotion in the clinic.

Indexed as

clinical symptomsCOVID-19Lianhua Qingwenretrospective studytotal effective ratetraditional Chinese medicine (TCM) treatment

Identifiers

PMID35273735
PMCPMC8902566

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.