Evidence map›Paper›PMID 35273713›Full record

ArticleAmerican journal of translational research2022

The first study of epidemiology of adolescent idiopathic scoliosis shows lower prevalence in females of Jammu and Kashmir, India.

Hemender Singh, Shipra, Varun Sharma, Indu Sharma, Akash Sharma, Sonakshi Modeel, Nital Gupta, Geetanjali Gupta, Ajay K Pandita, Mohammad Farooq Butt and 6 more

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  3. ESR1 as a candidate gene for adolescent idiopathic scoliosis pathogenesis in North-West Indian population.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Hemender SinghHuman Genetics Research Group, School of Biotechnology, Shri Mata Vaishno Devi University Katra, Jammu and Kashmir, India.
ShipraHuman Genetics Research Group, School of Biotechnology, Shri Mata Vaishno Devi University Katra, Jammu and Kashmir, India.
Varun SharmaHuman Genetics Research Group, School of Biotechnology, Shri Mata Vaishno Devi University Katra, Jammu and Kashmir, India.
Indu SharmaHuman Genetics Research Group, School of Biotechnology, Shri Mata Vaishno Devi University Katra, Jammu and Kashmir, India.
Akash SharmaHuman Genetics Research Group, School of Biotechnology, Shri Mata Vaishno Devi University Katra, Jammu and Kashmir, India.
Sonakshi ModeelHuman Genetics Research Group, School of Biotechnology, Shri Mata Vaishno Devi University Katra, Jammu and Kashmir, India.
Nital GuptaDepartment of Health and Family Welfare Union Territory, Jammu and Kashmir, India.
Geetanjali GuptaDepartment of Radiology, Shri Mata Vaishno Devi Narayana Superspeciality Hospital Katra, Jammu and Kashmir, India.
Ajay K PanditaAccidental Hospital Chowki Choura, Jammu, Jammu and Kashmir, India.
Mohammad Farooq ButtDepartment of Orthopedics, Government Medical College Jammu, Jammu and Kashmir, India.
Rajesh SharmaDepartment of Radio-Diagnosis, Government Medical College Jammu, Jammu and Kashmir, India.
Sarla PanditaRadiology Section, Chest Disease Hospital Bakshi Nagar, Jammu, Jammu and Kashmir, India.
Vinod SinghHuman Genetics Research Group, School of Biotechnology, Shri Mata Vaishno Devi University Katra, Jammu and Kashmir, India.
Ekta RaiHuman Genetics Research Group, School of Biotechnology, Shri Mata Vaishno Devi University Katra, Jammu and Kashmir, India.
Shiro IkegawaLaboratory for Bone and Joint Diseases, Center for Integrative Medical Sciences RIKEN, Tokyo, Japan.
Swarkar SharmaHuman Genetics Research Group, School of Biotechnology, Shri Mata Vaishno Devi University Katra, Jammu and Kashmir, India.
Government Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIS is a heterogeneous 3D spinal deformity with Cobb angle ≥10°. It affects children in the age group of 10-16 years globally with 2-3% prevalence and significant female predominance. The exact etiology of AIS is not known however, it is supposed to be associated with factors such as anthropometric, metabolic, neuromuscular abnormalities and genetics.

objectivesTo determine the prevalence of AIS and association of anthropometric factors with AIS in the studied population group. METHODOLOGY: Scoliosis screening of 9,500 individuals was carried out at different educational institutions of Jammu region in Jammu and Kashmir, India using a scoliosis-meter. The subjects were later examined radiologically.

resultsIn population of the region, AIS was most prevalent among all types of scoliosis with overall prevalence of 0.61%. The prevalence was observed to be lower in females (0.31%) than males (0.88%). Based on angle of trunk rotation (ATR), lumbar curves were more prevalent than thoracic curves. Average Cobb angle in males and females were 24.9° and 22.6°, respectively. BMI showed significant association with AIS in the age group of 12-16 years (

conclusionsThe AIS patients in the Jammu region of India have unique clinical features. In contrast to the global prevalence data, the prevalence of AIS in females in the region was less in comparison to males. Based on epidemiological literature and our findings, we hypothesized that genetic factors might be a major contributor in the AIS pathogenesis along with other confounding factors such as height, BMI, ethnicity, etc.

Indexed as

Adolescent idiopathic scoliosisangle of trunk rotationBMICobb angleJammu and Kashmirprevalence

Identifiers

PMID35273713
PMCPMC8902575
OpenAlexW4226033361

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.