ArticleFrontiers in endocrinology2022
Simultaneous Quantitative Susceptibility Mapping of Articular Cartilage and Cortical Bone of Human Knee Joint Using Ultrashort Echo Time Sequences.
Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Ultrashort Echo Time Quantitative Susceptibility Source Separation in Musculoskeletal System: A Feasibility Study.Journal of imaging · 2026Article
- Addressing fatty tissue in quantitative susceptibility mapping of human knee cartilage.Magma (New York, N.Y.) · 2025Article
- Effects of Motion in Ultrashort Echo Time Quantitative Susceptibility Mapping for Musculoskeletal Imaging.Journal of imaging · 2025Article
- Quantitative MRI methods for the assessment of structure, composition, and function of musculoskeletal tissues in basic research and preclinical applications.Magma (New York, N.Y.) · 2024Review
- QSM Throughout the Body.Journal of magnetic resonance imaging : JMRI · 2023Review
- Articular Cartilage Assessment Using Ultrashort Echo Time MRI: A Review.Frontiers in endocrinology · 2022Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: It is of great clinical importance to assess the microstructure of the articular cartilage and cortical bone of the human knee joint. While quantitative susceptibility mapping (QSM) is a promising tool for investigating the knee joint, however, previous QSM studies using conventional gradient recalled echo sequences or ultrashort echo time (UTE) sequences only focused on mapping the magnetic susceptibility of the articular cartilage or cortical bone, respectively. Simultaneously mapping the underlying susceptibilities of the articular cartilage and cortical bone of human Method: Three-dimensional multi-echo radial UTE sequences with the shortest TE of 0.07 msec and computed tomography (CT) were performed on the bilateral knee joints of five healthy volunteers for this prospective study. UTE-QSM was reconstructed from the local field map after water-fat separation and background field removal. Spearman's correlation analysis was used to explore the relationship between the magnetic susceptibility and CT values in 158 representative regions of interest of cortical bone. Result: The susceptibility properties of the articular cartilage and cortical bone were successfully quantified by UTE-QSM. The laminar structure of articular cartilage was characterized by the difference of susceptibility value in each layer. Susceptibility was mostly diamagnetic in cortical bone. A significant negative correlation (r=-0.43, p<0.001) between the susceptibility value and CT value in cortical bone was observed. Conclusion: UTE-QSM enables simultaneous susceptibility mapping of the articular cartilage and cortical bone of human
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.