Evidence map›Paper›PMID 35273506›Full record

ReviewFrontiers in pharmacology2022

Autophagy-Inflammation Interplay During Infection: Balancing Pathogen Clearance and Host Inflammation.

Yuqian Pang, Lanxi Wu, Cheng Tang, Hongna Wang, Yongjie Wei

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 78 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Dual-function cytokines as modulators of autophagy: reprogramming inflammatory resolution in severe COVID-19.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  7. Article
  8. Autophagy andFrontiers in cellular and infection microbiology · 2026
    Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Developing Endogenous Autophagy Reporters inInternational journal of molecular sciences · 2025
    Article
  15. Cell death pathways in response toInfection and immunity · 2025
    Review
  16. ATG9 inhibitsAutophagy · 2025
    Article
  17. Review
  18. Article
  19. Article
  20. Functional interplay between non-canonical inflammasomes and autophagy in inflammatory responses and diseases.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yuqian PangAffiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China.
Lanxi WuAffiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China.
Cheng TangAffiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China.
Hongna WangAffiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China.
Yongjie WeiAffiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China.
Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is an essential immune response of the host against infections but is often over-activated, leading to a variety of disorders. Autophagy, a conserved degradation pathway, also protects cells by capturing intracellular pathogens that enter the cell and transporting them to the lysosome for clearance. Dysfunctional autophagy is often associated with uncontrolled inflammatory responses during infection. In recent years, more and more research has focused on the crosstalk between autophagy and inflammation. In this paper, we review the latest research advances in this field, hoping to gain insight into the mechanisms by which the body balances autophagy and inflammation in infections and how this mechanism can be used to fight infections better.

Indexed as

autophagybacteriainfectioninflammasomeinflammationmicrobialvirus

Identifiers

PMID35273506
PMCPMC8902503
OpenAlexW4212939496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.