Evidence map›Paper›PMID 35273283›Full record

ArticleScientific reports2022

An assessment of the rescue action of resveratrol in parkin loss of function-induced oxidative stress in Drosophila melanogaster.

Adeola O Adedara, Ayoade D Babalola, Flora Stephano, Ifeoluwa O Awogbindin, James O Olopade, João B T Rocha, Alexander J Whitworth, Amos O Abolaji

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Kaempferol fromToxicology reports · 2026
    Article
  3. Article
  4. Biology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. International journal of molecular sciences · 2023
    Review
  15. Antidiabetes study ofJournal of Taibah University Medical Sciences · 2023
    Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Adeola O AdedaraDrosophila Laboratory, Molecular Drug Metabolism and Toxicology Unit, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Ayoade D BabalolaCancer Research and Molecular Biology Laboratory, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Flora StephanoDepartment of Zoology and Wildlife Conservation, College of Natural and Applied Sciences, University of Dar es Salaam, Dar es Salaam, Tanzania.
Ifeoluwa O AwogbindinDrosophila Laboratory, Molecular Drug Metabolism and Toxicology Unit, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
James O OlopadeDepartment of Veterinary Anatomy, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
João B T RochaDepartment of Biochemistry and Molecular Biology, Federal University of Santa Maria, R/S, Camobi, Santa Maria, Brazil.
Alexander J WhitworthMRC Mitochondria Biology Unit, University of Cambridge, Cambridge, UK. a.whitworth@mrc-mbu.cam.ac.uk.
Amos O AbolajiDrosophila Laboratory, Molecular Drug Metabolism and Toxicology Unit, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria. ao.abolaji@ui.edu.ng.
University of Ibadan · NGUniversidade Federal de Santa Maria · BRUniversity of Cambridge · GBUniversity of Dar es Salaam · TZ

Funding

Medical Research Council MC_UU_00015/6
6 · The paper itself

Abstract

Loss-of-function mutations in parkin is associated with onset of juvenile Parkinson's disease (PD). Resveratrol is a polyphenolic stilbene with neuroprotective activity. Here, we evaluated the rescue action of resveratrol in parkin mutant D. melanogaster. The control flies (w

Indexed as

Drosophila melanogasterDrosophila ProteinsAcetylcholinesteraseAnimalsAntioxidantsOxidative StressResveratrolSulfhydryl CompoundsSuperoxide Dismutase-1Ubiquitin-Protein LigasesAcetylcholinesteraseAntioxidantsDrosophila ProteinsResveratrolSulfhydryl CompoundsSuperoxide Dismutase-1Ubiquitin-Protein Ligases

Identifiers

PMID35273283
PMCPMC8913626
OpenAlexW4220821309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.