Evidence map›Paper›PMID 35273252›Full record

ArticleScientific reports2022

Combining graph neural networks and spatio-temporal disease models to improve the prediction of weekly COVID-19 cases in Germany.

Cornelius Fritz, Emilio Dorigatti, David Rügamer

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Spatio-temporal epidemic forecasting with graph-based transformer.International journal of health geographics · 2026
    Article
  5. Article
  6. Article
  7. Opioid Overdose Death Prediction with Graph Neural Networks.medRxiv : the preprint server for health sciences · 2026
    Article
  8. Article
  9. Opioid Overdose Death Prediction with Graph Neural Networks.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026
    Article
  10. Inferring pathogen superspreading potential using early spatial spread patterns.medRxiv : the preprint server for health sciences · 2025
    Article
  11. Review
  12. Article
  13. Graph Artificial Intelligence in Medicine.Annual review of biomedical data science · 2024
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Spatial analysis and risk mapping ofParasite epidemiology and control · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cornelius Fritz *Department of Statistics, Ludwig Maximilian Universität, München, Germany.
Emilio Dorigatti *Department of Statistics, Ludwig Maximilian Universität, München, Germany.
David RügamerDepartment of Statistics, Ludwig Maximilian Universität, München, Germany. david.ruegamer@stat.uni-muenchen.de.

Funding

Bundesministerium für Bildung und Forschung 01IS18036AHelmholtz-Gemeinschaft HIDSS-0006
6 · The paper itself

Abstract

During 2020, the infection rate of COVID-19 has been investigated by many scholars from different research fields. In this context, reliable and interpretable forecasts of disease incidents are a vital tool for policymakers to manage healthcare resources. In this context, several experts have called for the necessity to account for human mobility to explain the spread of COVID-19. Existing approaches often apply standard models of the respective research field, frequently restricting modeling possibilities. For instance, most statistical or epidemiological models cannot directly incorporate unstructured data sources, including relational data that may encode human mobility. In contrast, machine learning approaches may yield better predictions by exploiting these data structures yet lack intuitive interpretability as they are often categorized as black-box models. We propose a combination of both research directions and present a multimodal learning framework that amalgamates statistical regression and machine learning models for predicting local COVID-19 cases in Germany. Results and implications: the novel approach introduced enables the use of a richer collection of data types, including mobility flows and colocation probabilities, and yields the lowest mean squared error scores throughout the observational period in the reported benchmark study. The results corroborate that during most of the observational period more dispersed meeting patterns and a lower percentage of people staying put are associated with higher infection rates. Moreover, the analysis underpins the necessity of including mobility data and showcases the flexibility and interpretability of the proposed approach.

Indexed as

Epidemiological ModelsNeural Networks, ComputerSpatio-Temporal AnalysisAdolescentAdultCOVID-19FemaleGermanyHumansMachine LearningMaleMiddle AgedYoung Adult

Identifiers

PMID35273252
PMCPMC8913758

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.