ArticleScientific reports2022
Probing elastic anisotropy of human skin in vivo with light using non-contact acoustic micro-tapping OCE and polarization sensitive OCT.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Super-resolution wave-dispersion analysis in optical coherence elastography using multiple signal classification (MUSIC).Biomedical optics express · 2026Article
- Simple non-invasive in vivo measurement of stress difference in the skin.Biomechanics and modeling in mechanobiology · 2026Article
- Depth-resolved phase velocity estimation in layered tissue based on an efficient additive attention network with surface acoustic wave - optical coherence elastography.Biomedical optics express · 2026Article
- TowardFrontiers in bioengineering and biotechnology · 2026Review
- Reconstruction of tensile and shear elastic moduli in anisotropic nearly incompressible media using Rayleigh wave phase and group velocities.Journal of biomedical optics · 2025Article
- Design and implementation of an integrated scanning protocol for multimodal functional OCT.Biomedical optics express · 2025Article
- Parameterization of the stress-strain relation for modeling wave propagation in nearly incompressible transversely isotropic materials.The Journal of the Acoustical Society of America · 2024Article
- Asynchronous, semi-reverberant elastography.Optica · 2024Article
- Full-field noise-correlation elastography for in-plane mechanical anisotropy imaging.Biomedical optics express · 2024Article
- Correlation analysis between texture features and elasticity of skin hyperspectral images in the near-infrared band.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Innervation of an Ultrasound-Mediated PVDF-TrFE Scaffold for Skin-Tissue Engineering.Biomimetics (Basel, Switzerland) · 2023Article
- Possible depth-resolved reconstruction of shear moduli in the cornea following collagen crosslinking (CXL) with optical coherence tomography and elastography.Biomedical optics express · 2023Article
- Article
- Acoustic Micro-Tapping Optical Coherence Elastography to Quantify Corneal Collagen Cross-Linking: An Ex Vivo Human Study.Ophthalmology science · 2023Article
- Label-free optical interferometric microscopy to characterize morphodynamics in living plants.Frontiers in plant science · 2023Review
- Recent advances in optical elastography and emerging opportunities in the basic sciences and translational medicine [Invited].Biomedical optics express · 2023Review
- Spatial resolution in optical coherence elastography of bounded media.Biomedical optics express · 2022Article
- In vivo stiffness measurement of epidermis, dermis, and hypodermis using broadband Rayleigh-wave optical coherence elastography.Acta biomaterialia · 2022Article
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Authors and funding
10 authors.
Funding
Abstract
Skin broadly protects the human body from undesired factors such as ultraviolet radiation and abrasion and helps conserve body temperature and hydration. Skin's elasticity and its level of anisotropy are key to its aesthetics and function. Currently, however, treatment success is often speculative and subjective, and is rarely based on skin's elastic properties because there is no fast and accurate non-contact method for imaging of skin's elasticity. Here we report on a non-contact and non-invasive method to image and characterize skin's elastic anisotropy. It combines acoustic micro-tapping optical coherence elastography (AμT-OCE) with a nearly incompressible transversely isotropic (NITI) model to quantify skin's elastic moduli. In addition, skin sites were imaged with polarization sensitive optical coherence tomography (PS-OCT) to help define fiber orientation. Forearm skin areas were investigated in five volunteers. Results clearly demonstrate elastic anisotropy of skin in all subjects. AμT-OCE has distinct advantages over competitive techniques because it provides objective, quantitative characterization of skin's elasticity without contact, which opens the door for broad translation into clinical use. Finally, we demonstrate that a combination of multiple OCT modalities (structural OCT, OCT angiography, PS-OCT and AμT-OCE) may provide rich information about skin and can be used to characterize scar.
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