ArticleNature communications2022
Tunable and scalable fabrication of block copolymer-based 3D polymorphic artificial cell membrane array.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed.
- Construction of a dual-compartment hydrogel by protein-based triblock copolymer for theMaterials today. Bio · 2026Article
- Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Exploring the Application of Advanced Chromatographic Methods to Characterize the Surface Physicochemical Properties and Transition Phenomena of Polystyrene-Molecules (Basel, Switzerland) · 2024Article
- A nondestructive membrane engineering method using an amphiphilic polymer.Protein science : a publication of the Protein Society · 2024Article
- Looking both ways: Electroactive biomaterials with bidirectional implications for dynamic cell-material crosstalk.Biophysics reviews · 2024Review
- Morphology Engineering of the Asymmetric PS-ACS applied polymer materials · 2023Article
- Liquid Phase Infiltration of Block Copolymers.Polymers · 2022Review
- Bio-Inspired Robots and Structures toward Fostering the Modernization of Agriculture.Biomimetics (Basel, Switzerland) · 2022Review
- Enhancing female fertility by biomaterial-based regeneration of uterine tubes.Cell transplantationReview
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Owing to their excellent durability, tunable physical properties, and biofunctionality, block copolymer-based membranes provide a platform for various biotechnological applications. However, conventional approaches for fabricating block copolymer membranes produce only planar or suspended polymersome structures, which limits their utilization. This study is the first to demonstrate that an electric-field-assisted self-assembly technique can allow controllable and scalable fabrication of 3-dimensional block copolymer artificial cell membranes (3DBCPMs) immobilized on predefined locations. Topographically and chemically structured microwell array templates facilitate uniform patterning of block copolymers and serve as reactors for the effective growth of 3DBCPMs. Modulating the concentration of the block copolymer and the amplitude/frequency of the electric field generates 3DBCPMs with diverse shapes, controlled sizes, and high stability (100% survival over 50 days). In vitro protein-membrane assays and mimicking of human intestinal organs highlight the potential of 3DBCPMs for a variety of biological applications such as artificial cells, cell-mimetic biosensors, and bioreactors.
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Registered trials
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