ReviewNature reviews. Disease primers2022
Hypertensive eye disease.
Review in Nature reviews. Disease primers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- Does Nocturnal Blood Pressure Matter in Retinal Small Vessels? A Systematic Review and Meta-Analysis of the Literature.Current hypertension reports · 2025Pooled it
- Impact of Patient Characteristics and Surgery-Related Risk Factors on Endophthalmitis after Cataract surgery: A Meta-Analysis.Ophthalmic research · 2025Pooled it
- A plasma proteomic atlas of the ocular disease phenome.Science China. Life sciences · 2026Article
- Advanced Multi-Level Bidirectional Attention Network for Retinal Vessel Segmentation.Interdisciplinary sciences, computational life sciences · 2026Article
- Pathophysiology and Clinical Relevance of Microvascular Remodeling in Arterial Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Review
- Wireless knee joint monitoring using biodegradable single-ended pressure sensor in osteoarthritis management.Science advances · 2026Article
- Proportion and risk factors of retinal changes in pregnant women with HELLP syndrome.BMC pregnancy and childbirth · 2026Article
- Adaptive Optics RTX1 Imaging for Early Detection of Retinal Vascular Remodeling in Hypertensive Retinopathy: A Review.Journal of clinical medicine · 2026Review
- Associations of Frailty Index and Composite Dietary Antioxidant Index With Major Ocular Diseases and Analysis of Component Contributions: A Cross-Sectional Study.Translational vision science & technology · 2026Article
- Retinal Dysfunction in Hypertensive Patients with Atherosclerotic Plaque Detected by Carotid Doppler Ultrasound: An Optical Coherence Tomography Angiography Assessment.Life (Basel, Switzerland) · 2026Article
- Single-nucleus RNA sequencing reveals Cntnap2Journal of advanced research · 2026Article
- Retinal BioAge is associated with indicators of cardiovascular-kidney-metabolic syndrome in UK and US populations.Scientific reports · 2026Article
- Normative Database and Determinants of Retinal and Choroidal Vessel Density in Tibetan Children.Children (Basel, Switzerland) · 2026Article
- Association of diurnal blood pressure patterns with heart rate variability and retinopathy in patients with essential hypertension.Scientific reports · 2026Article
- Stroke risk in patients with hypertensive retinopathy: a systematic review and meta-analysis.BMJ neurology open · 2026Article
- Greenspace Exposure and the Incidence of Ocular and Adnexal Diseases: Novel Findings from a Large Prospective Cohort Study.Health data science · 2026Article
- Plasma Protein Mediation of the Association Between Blood Pressure and Retinal Vascular Occlusion.Translational vision science & technology · 2025Observational
- From retina to brain: how deep learning closes the gap in silent stroke screening.NPJ digital medicine · 2025Article
- A comprehensive narrative review on precision medicine approach to hypertension: exploring the role of genetics, epigenetics, microbiome, and artificial intelligence.Journal of health, population, and nutrition · 2025Review
- Hypertensive retinopathy: The need for a change in perspective.Indian journal of ophthalmology · 2025Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 6 countries.
Funding
Abstract
Hypertensive eye disease includes a spectrum of pathological changes, the most well known being hypertensive retinopathy. Other commonly involved parts of the eye in hypertension include the choroid and optic nerve, sometimes referred to as hypertensive choroidopathy and hypertensive optic neuropathy. Together, hypertensive eye disease develops in response to acute and/or chronic elevation of blood pressure. Major advances in research over the past three decades have greatly enhanced our understanding of the epidemiology, systemic associations and clinical implications of hypertensive eye disease, particularly hypertensive retinopathy. Traditionally diagnosed via a clinical funduscopic examination, but increasingly documented on digital retinal fundus photographs, hypertensive retinopathy has long been considered a marker of systemic target organ damage (for example, kidney disease) elsewhere in the body. Epidemiological studies indicate that hypertensive retinopathy signs are commonly seen in the general adult population, are associated with subclinical measures of vascular disease and predict risk of incident clinical cardiovascular events. New technologies, including development of non-invasive optical coherence tomography angiography, artificial intelligence and mobile ocular imaging instruments, have allowed further assessment and understanding of the ocular manifestations of hypertension and increase the potential that ocular imaging could be used for hypertension management and cardiovascular risk stratification.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.