Evidence map›Paper›PMID 35273084›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022

A Non-Nuclear NF-κB Modulates Alcohol Sensitivity But Not Immunity.

Thilini P Wijesekera, Zheng Wu, Nicole P Stephens, Rahul Godula, Linda Kao Lew, Nigel S Atkinson

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Thilini P WijesekeraDepartment of Neuroscience and The Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas 78712.
Zheng WuDepartment of Neuroscience and The Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas 78712.
Nicole P StephensDepartment of Neuroscience and The Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas 78712.
Rahul GodulaDepartment of Neuroscience and The Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas 78712.
Linda Kao LewDepartment of Neuroscience and The Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas 78712.
Nigel S AtkinsonDepartment of Neuroscience and The Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas 78712 nigela@utexas.edu.ORCID 0000-0001-8963-7478
The University of Texas at Austin · US

Funding

Epigenetic modification as a mechanism to produce functional toleranceR01AA018037 · NIAAA · UNIVERSITY OF TEXAS AT AUSTIN · PI ATKINSON, NIGEL S · 2008 to 2018
$3.3M
NIAAA NIH HHS R01 AA018037
6 · The paper itself

Abstract

NF-κB proteins are well known as transcription factors important in immune system activation. In this highly conserved role, they contribute to changes in behavior in response to infection and in response to a variety of other insults and experiences. In some mammalian neurons, NF-κBs can be found at the synapse and translocate to the nucleus to alter gene expression when activated by synaptic activity. Here, we demonstrate that, in

Indexed as

AlcoholismDrosophila ProteinsAnimalsDNA-Binding ProteinsDrosophilaDrosophila melanogasterFemaleImmunity, InnateMaleMammalsNF-kappa BNuclear ProteinsProtein IsoformsTranscription FactorsDif protein, DrosophilaDNA-Binding ProteinsDrosophila ProteinsNF-kappa BNuclear ProteinsProtein IsoformsTranscription Factorsalcohol sensitivitybehaviorDrosophilainnate immune systemneuroimmunesynapse

Identifiers

PMID35273084
PMCPMC9034786
OpenAlexW4220654402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.