Evidence map›Paper›PMID 35273083›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022

Formation of the Mouse Internal Capsule and Cerebral Peduncle: A Pioneering Role for Striatonigral Axons as Revealed in

Jacqueline M Ehrman, Paloma Merchan-Sala, Lisa A Ehrman, Bin Chen, Hee-Woong Lim, Ronald R Waclaw, Kenneth Campbell

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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  9. The transcription factorFrontiers in cell and developmental biology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jacqueline M EhrmanDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229.
Paloma Merchan-SalaDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229.
Lisa A EhrmanDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229.
Bin ChenDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California 95064.
Hee-Woong LimBiomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229.
Ronald R WaclawDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229.
Kenneth CampbellDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229 kenneth.campbell@cchmc.org.ORCID 0000-0001-5666-8008
Cincinnati Children's Hospital Medical Center · USUniversity of California, Santa Cruz · US

Funding

Molecular Mechanisms Controlling Formation of Basal Ganglia CircuitryR01MH090740 · NIMH · CINCINNATI CHILDRENS HOSP MED CTR · PI CAMPBELL, KENNETH J, WACLAW, RONALD R · 2010 to 2022
$4.8M
Lineage Progression of Cortical Neural Stem CellsR01NS089777 · NINDS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI CHEN, BIN · 2015 to 2025
$4.7M
Transcriptional regulation of neuronal identity and connectivityR01MH094589 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI CHEN, BIN · 2011 to 2021
$3.7M
Contributions of the striatal direct pathway to the formation of corticofugal axon trajectoriesF30MH123056 · NIMH · UNIVERSITY OF CINCINNATI · PI EHRMAN, JACQUELINE MARIE · 2020 to 2023
$181k
NIMH NIH HHS F30 MH123056NIMH NIH HHS R01 MH090740NIMH NIH HHS R01 MH094589NINDS NIH HHS R01 NS089777
6 · The paper itself

Abstract

The projection neurons of the striatum, the principal nucleus of the basal ganglia, belong to one of the following two major pathways: the striatopallidal (indirect) pathway or the striatonigral (direct) pathway. Striatonigral axons project long distances and encounter ascending tracts (thalamocortical) while coursing alongside descending tracts (corticofugal) as they extend through the internal capsule and cerebral peduncle. These observations suggest that striatal circuitry may help to guide their trajectories. To investigate the developmental contributions of striatonigral axons to internal capsule formation, we have made use of

Indexed as

Autism Spectrum DisorderCerebral PeduncleAnimalsAxonsCerebral CortexInternal CapsuleMiceMice, KnockoutMice, TransgenicNeural PathwaysThalamusaxon guidanceaxon outgrowthcerebral cortexdevelopmentstriatumthalamus

Identifiers

PMID35273083
PMCPMC9034787
OpenAlexW4220682824

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.