Evidence map›Paper›PMID 35272477›Full record

ArticleThe Journal of urology2022

The Effect of Different Types of Prostate Biopsy Techniques on Post-Biopsy Infectious Complications.

Sofie C M Tops, Justin G A Grootenhuis, Anouk M Derksen, Federica Giardina, Eva Kolwijck, Heiman F L Wertheim, Diederik M Somford, J P Michiel Sedelaar

Open access · hybridAbstract read
In one paragraph

Article in The Journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Efficacy of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
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  6. End-to-end [Abdominal radiology (New York) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sofie C M TopsDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
Justin G A GrootenhuisDepartment of Urology, Radboud University Medical Center, Nijmegen, The Netherlands.
Anouk M DerksenDepartment of Urology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Federica GiardinaDepartment for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.
Eva KolwijckDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
Heiman F L WertheimDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
Diederik M SomfordDepartment of Urology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
J P Michiel SedelaarDepartment of Urology, Radboud University Medical Center, Nijmegen, The Netherlands.
Radboud University Nijmegen · NLCanisius-Wilhelmina Ziekenhuis · NLRadboud University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of our study was to compare infectious complication rates between different prostate biopsy techniques with various number of biopsy cores. MATERIALS AND

methodsIn this retrospective study, all patients from 2 hospitals who underwent prostate biopsy between 2012 and 2019 were identified. Cohorts with different types of prostate biopsies were compiled within these hospitals. Primary outcome measure was any registered infectious complication within 7 days post-biopsy. Secondary outcomes were infectious complications within 30 days, hospitalization and bacteremia. To compare the risk of infection following different prostate biopsy techniques, data was fitted into a logistic regression model adjusting for potential confounders.

resultsIn total, 4,233 prostate biopsies in 3,707 patients were included. After systematic transrectal ultrasound-guided prostate biopsy (TRUSPB; 12±1.4 biopsy cores), 4.0% (2,607) of all patients had infectious complications within 7 days post-biopsy. Transperineal magnetic resonance imaging (MRI)-ultrasound fusion guided prostate biopsy (16±3.7 biopsy cores) was associated with significantly lower infection rates than systematic TRUSPB (adjusted OR: 0.29 [0.09-0.73] 95% confidence interval [CI]). Transrectal targeted MRI-ultrasound fusion guided prostate biopsy (3.1±0.8 biopsy cores) and transrectal targeted in-bore MRI guided prostate biopsy (2.8±0.8 biopsy cores) also showed fewer infectious complications than systematic TRUSPB (adjusted OR: 0.41 [0.12-1.12] 95% CI and 0.68 [0.37-1.20] 95% CI, respectively).

conclusionsTransperineal prostate biopsy, or transrectal prostate biopsy with reduced number of biopsy cores, could lower the risk of infectious complications.

Indexed as

Magnetic Resonance Imaging, InterventionalProstatic NeoplasmsHumansImage-Guided BiopsyMaleProstateRetrospective StudiesUltrasonography, Interventionalbiopsyimage-guided biopsyinfectionsperineumrectum

Identifiers

PMID35272477
PMCPMC12721679
OpenAlexW4220759998

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.