ArticleAnnals of coloproctology2023
Outcomes of side-to-end versus end-to-end colorectal anastomosis in nonemergent sigmoid and rectal cancers: a randomized controlled clinical trial.
Article in Annals of coloproctology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Linear versus circular stapler for colorectal anastomosis in laparoscopic sigmoidectomy: a retrospective comparative study.Annals of coloproctology · 2026Article
- Updates in surgery for colorectal cancer: incidence and risk factors for acute anastomotic leak-a retrospective study.Updates in surgery · 2026Article
- Short-term Outcomes of Linear vs. Circular Stapling for Esophagojejunostomy in Gastric Cancer: an Inverse Probability of Treatment Weighting Analysis.Journal of gastric cancer · 2025Article
- Risk Factors for Sigmoid Colonic Anastomosis: A Comparative and Cross-Sectional Analysis.Therapeutics and clinical risk management · 2025Article
- The impact of powered circular staplers on anastomotic leak in left-sided colorectal cancer surgeries.Surgical endoscopy · 2024Article
- Minimally invasive left colectomy with total intracorporeal anastomosis versus extracorporeal anastomosis. A single center cohort study. Stage 2b IDEAL framework for evaluating surgical innovation.Langenbeck's archives of surgery · 2024Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe outcomes of open colorectal anastomosis of side-to-end versus end-to-end in nonemergent sigmoid and rectal cancer surgery in adults were compared.
methodsA randomized controlled trial on individuals with sigmoid and rectal cancers was conducted between September 2016 and September 2018.
resultsThe mean age was 62.58±12.3 years in the side-to-end anastomotic (SEA) group and 61.03±13.98 years in the end-to-end anastomotic (EEA) group. Except for the operative time, intraoperative data revealed no significant differences between the studied groups, and the SEA group revealed that the mean anastomotic time was significantly shorter. Perioperative blood loss, length of stay, reoperation, inpatient death, infection, and bleeding were significantly associated with leakage. There is a statistically significant change regarding the range of bowel frequency in the EEA group only (P=0.04). There is a statistically significant difference regarding incontinence for flatus in the SEA group only (P≤0.001). A statistically significant change in both groups regards incontinence for liquid stools (P≤0.001) and clustering of stools (P≤0.001 and P=0.043). The quality of life in the SEA group significantly dropped at 6 months and then returned to baseline as regards to physical well-being (PWB), functional well-being (FWB), and colorectal cancer symptoms (CCS) with no difference as regards SWB and EWB, while in the EEA group, the exact change happened only as regard PWB and FWB, but SWB and CCS percentage did not return to baseline.
conclusionThe SEA group offers a safe alternative approach to the EEA group.
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