Evidence map›Paper›PMID 35272344›Full record

ArticleFemale pelvic medicine & reconstructive surgery2022

Prevalence of Overactive Bladder Symptoms Among Women With Interstitial Cystitis/Bladder Pain Syndrome.

Alexandra Dubinskaya, Lauren N Tholemeier, Tyler Erickson, Amanda M De Hoedt, Kamil E Barbour, Jayoung Kim, Stephen J Freedland, Jennifer T Anger

Open access · greenAbstract read
In one paragraph

Article in Female pelvic medicine & reconstructive surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. 2025 Canadian Urological Association Guideline: Selected treatment recommendations for interstitial cystitis/bladder pain syndrome.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
    Article
  4. Associations of pain in young men presenting with lower urinary tract symptoms.Indian journal of urology : IJU : journal of the Urological Society of India
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Alexandra DubinskayaFrom the Division of Urology, Cedars-Sinai Medical Center.
Lauren N TholemeierDepartment of Obstetrics and Gynecology, Cedars-Sinai Blvd, Los Angeles, CA.
Tyler EricksonUrology Section, Durham Veterans Affairs Health Care System, Durham, NC.
Amanda M De HoedtUrology Section, Durham Veterans Affairs Health Care System, Durham, NC.
Kamil E BarbourCenters for Disease Control and Prevention, Atlanta, GA.
Jayoung KimFrom the Division of Urology, Cedars-Sinai Medical Center.
Stephen J Freedland
Jennifer T AngerUC San Diego Department of Urology, La Jolla, CA.
Durham VA Health Care System · USCedars-Sinai Medical Center · USCenters for Disease Control and Prevention · US

Funding

The Epidemiology of Interstitial Cystitis in a Nationwide Multiethnic VA CohortU01DP006079 · DP · CEDARS-SINAI MEDICAL CENTER · PI ANGER, JENNIFER TASH, FREEDLAND, STEPHEN JAY · 2015 to 2019
$3.8M
ACL HHS U01DP006079NCCDPHP CDC HHS U01 DP006079
6 · The paper itself

Abstract

importanceSymptoms of urinary frequency, urgency, and urinary leakage are characteristic of overactive bladder (OAB) syndrome. However, frequency and urgency symptoms are also present in most patients with interstitial cystitis/bladder pain syndrome (IC/BPS).

objectiveOur objective was to describe the urge incontinence among women with IC/BPS, which may indicate true overlap of OAB and IC/BPS. STUDY

designThis is a prospective study of women with IC/BPS diagnosed clinically in the Veterans Affairs Health Care system. Patients completed the OAB and Female Genitourinary Pain Index (F-GUPI) questionnaires. Questions from the OAB questionnaire were used to analyze symptoms of urinary urgency and urge incontinence. Pain symptoms, urinary symptoms, and impact on quality of life were assessed based on the F-GUPI. Patient demographics, comorbidities, and symptoms were reviewed.

resultsWithin the cohort of 144 women with IC/BPS, 100 (69%) had urinary leakage associated with the strong desire to void and were more likely to have incontinence compared with healthy controls (P < 0.001). The IC/BPS group also had higher total and pain scores on the F-GUPI (P < 0.001), but pain scores were not affected by the presence of incontinence (P = 0.478).

conclusionsThe prevalence of OAB symptoms of urinary leakage is high among women with IC/BPS. This may explain the efficacy of OAB medication and third-line therapies in this population.

Indexed as

Cystitis, InterstitialUrinary Bladder, OveractiveUrinary IncontinenceFemaleHumansPelvic PainPrevalenceProspective StudiesQuality of LifeUrinary Incontinence, Urge

Identifiers

PMID35272344
PMCPMC8928040
OpenAlexW4220846743

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.