Evidence map›Paper›PMID 35271719›Full record

ArticleJournal of insect science (Online)2022

Na+/K+-ATPase Activation by cAMP in the Midgut of Lutzomyia longipalpis (Lutz & Neiva, 1912; Diptera: Psychodidae).

Denise Barguil Nepomuceno, Grasielle Caldas DÁvila Pessoa, Ricardo Nascimento Araújo, Leonardo Barbosa Koerich, Maurício Roberto Viana Sant'Anna, Marcos Horácio Pereira, Nelder Figueiredo Gontijo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of insect science (Online), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Denise Barguil NepomucenoLaboratório de Fisiologia de Insetos Hematófagos, Departamento de Parasitologia-ICB, Universidade Federal de Minas Gerais-UFMG, Belo Horizonte, MG, Brazil.
Grasielle Caldas DÁvila PessoaLaboratório de Fisiologia de Insetos Hematófagos, Departamento de Parasitologia-ICB, Universidade Federal de Minas Gerais-UFMG, Belo Horizonte, MG, Brazil.
Ricardo Nascimento AraújoLaboratório de Fisiologia de Insetos Hematófagos, Departamento de Parasitologia-ICB, Universidade Federal de Minas Gerais-UFMG, Belo Horizonte, MG, Brazil.
Leonardo Barbosa KoerichLaboratório de Fisiologia de Insetos Hematófagos, Departamento de Parasitologia-ICB, Universidade Federal de Minas Gerais-UFMG, Belo Horizonte, MG, Brazil.
Maurício Roberto Viana Sant'AnnaLaboratório de Fisiologia de Insetos Hematófagos, Departamento de Parasitologia-ICB, Universidade Federal de Minas Gerais-UFMG, Belo Horizonte, MG, Brazil.
Marcos Horácio PereiraLaboratório de Fisiologia de Insetos Hematófagos, Departamento de Parasitologia-ICB, Universidade Federal de Minas Gerais-UFMG, Belo Horizonte, MG, Brazil.
Nelder Figueiredo GontijoLaboratório de Fisiologia de Insetos Hematófagos, Departamento de Parasitologia-ICB, Universidade Federal de Minas Gerais-UFMG, Belo Horizonte, MG, Brazil.ORCID 0000-0003-3357-2497
Universidade Federal de Minas Gerais · BR

Funding

Conselho Nacional de Desenvolvimento Cientıfico e TecnológicoCoordenação de Aperfeiçoamento de Pessoal de Nível SuperiorFundação de Amparo à Pesquisa do Estado de Minas GeraisInstituto Nacional de Ciência e Tecnologia-Entomologia Molecular
6 · The paper itself

Abstract

Lutzomyia longipalpis (Lutz & Neiva, 1912) females have been intensively studied regarding the regulation of midgut pH. The mechanisms involved in pH regulation are complex, and some aspects remain to be clarified. Here, we investigated the role of the Na+/K+-ATPase pump as an electrochemical potential generator and its modulation by the second messenger cAMP in the midgut of female L. longipalpis. Our results suggest that not only may Na+/K+-ATPase be the main generator of an electrochemical potential across membranes in the midgut of female L. longipalpis, but also its activity is positively regulated by cAMP. cAMP-mediated Na+/K+-ATPase pump activity might be necessary to maintain the transport of the nutrients produced during blood digestion.

Indexed as

PsychodidaeAdenosine TriphosphatasesAnimalsDigestive SystemFemaleAdenosine TriphosphatasescAMPmidgutNa+/K+-ATPasepHsandfly

Identifiers

PMID35271719
PMCPMC8912928
OpenAlexW4210942247

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.