Evidence map›Paper›PMID 35271703›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2023

Simultaneous relaxometry and morphometry of human brain structures with 3D magnetic resonance fingerprinting: a multicenter, multiplatform, multifield-strength study.

Shohei Fujita, Matteo Cencini, Guido Buonincontri, Naoyuki Takei, Rolf F Schulte, Issei Fukunaga, Wataru Uchida, Akifumi Hagiwara, Koji Kamagata, Yasuhiro Hagiwara and 4 more

Abstract readMulticenter Study
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Shohei FujitaDepartment of Radiology, Juntendo University, Tokyo, Japan.ORCID 0000-0003-4276-6226
Matteo CenciniImago7 Foundation, Pisa, Italy.
Guido BuonincontriImago7 Foundation, Pisa, Italy.
Naoyuki TakeiGE Healthcare, Tokyo, Japan.
Rolf F SchulteGE Healthcare, Munich, Germany.
Issei FukunagaDepartment of Radiology, Juntendo University, Tokyo, Japan.
Wataru UchidaDepartment of Radiology, Juntendo University, Tokyo, Japan.
Akifumi HagiwaraDepartment of Radiology, Juntendo University, Tokyo, Japan.
Koji KamagataDepartment of Radiology, Juntendo University, Tokyo, Japan.
Yasuhiro HagiwaraDepartment of Biostatistics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Yutaka MatsuyamaDepartment of Biostatistics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Osamu AbeDepartment of Radiology, The University of Tokyo, Tokyo, Japan.
Michela TosettiImago7 Foundation, Pisa, Italy.
Shigeki AokiDepartment of Radiology, Juntendo University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Relaxation times and morphological information are fundamental magnetic resonance imaging-derived metrics of the human brain that reflect the status of the underlying tissue. Magnetic resonance fingerprinting (MRF) enables simultaneous acquisition of T1 and T2 maps inherently aligned to the anatomy, allowing whole-brain relaxometry and morphometry in a single scan. In this study, we revealed the feasibility of 3D MRF for simultaneous brain structure-wise morphometry and relaxometry. Comprehensive test-retest scan analyses using five 1.5-T and three 3.0-T systems from a single vendor including different scanner types across 3 institutions demonstrated that 3D MRF-derived morphological information and relaxation times are highly repeatable at both 1.5 T and 3.0 T. Regional cortical thickness and subcortical volume values showed high agreement and low bias across different field strengths. The ability to acquire a set of regional T1, T2, thickness, and volume measurements of neuroanatomical structures with high repeatability and reproducibility facilitates the ability of longitudinal multicenter imaging studies to quantitatively monitor changes associated with underlying pathologies, disease progression, and treatments.

Indexed as

BrainMagnetic Resonance ImagingHumansImage Processing, Computer-AssistedMagnetic Resonance SpectroscopyReproducibility of Resultsquantitative MRIrelaxation timesT1T2thicknessvolume

Identifiers

PMID35271703
PMCPMC9890456

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.