ArticlePloS one2022
Biodegradable gelatin-based films with nisin and EDTA that inhibit Escherichia coli.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 25 citations in OpenAlex.
- Characterization, antibacterial properties, and application of gelatin films reinforced with smectite and illite clays for cherry fruit preservation.Food chemistry: X · 2025Article
- Functional Biopolymer Coatings with Nisin/Na-EDTA as an Active Agent: Enhancing Seafood Preservation.Foods (Basel, Switzerland) · 2025Article
- Characterization ofFood science & nutrition · 2024Article
- Synergistic effects of EDTA and lysozyme on the properties of hydroxypropyl starch nano antibacterial films.Current research in food science · 2024Article
- Use of Chitosan-Based Polyelectrolyte Complexes for Its Potential Application in Active Food Packaging: A Review of Recent Literature.International journal of molecular sciences · 2023Review
- Development and Characterization of Films with Propolis to Inhibit Mold Contamination in the Dairy Industry.Foods (Basel, Switzerland) · 2023Article
- Bioengineering of a Lactococcus lactis subsp. lactis strain enhances nisin production and bioactivity.PloS one · 2023Article
- Antimicrobial Active Packaging Containing Nisin for Preservation of Products of Animal Origin: An Overview.Foods (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, we developed gelatin-based films for active packaging with the ability to inhibit E. coli. We created these novel biodegradable gelatin-based films with a nisin-EDTA mix. FT-IR, TGA, and SEM analysis showed that nisin interacted with the gelatin by modifying its thermal stability and morphology. The use of nisin (2,500 IU/mL) with concentrations of Na-EDTA (1.052 M stock solution) distributed in the polymer matrix generated a significant decrease in the growth of E. coli when compared to the control. In freshly made films (t0), the growth of E. coli ATCC 25922 was reduced by approximately 3 logarithmic cycles. Two weeks after the films were made, a reduction in antimicrobial activity was observed in approximately 1, 1 and 3 logarithmic cycles of the films with 5%, 10% and 20% of the compound (nisin/Na-EDTA) distributed in the polymer matrix, respectively. This evidences an antimicrobial effect over time. Also, biodegradation tests showed that the films were completely degraded after 10 days. With all these results, an active and biodegradable packaging was successfully obtained to be potentially applied in perishable foods. These biodegradable, gelatin-based films are a versatile active packaging option. Further research on the barrier properties of these films is needed.
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Registered trials
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