Evidence map›Paper›PMID 35271462›Full record

ArticleAging2022

Centrosomal protein 290 is a novel prognostic indicator that modulates liver cancer cell ferroptosis via the

Yiru Shan, Guang Yang, Qiuhong Lu, Xiangyu Hu, Dongwei Qi, Yehan Zhou, Yin Xiao, Li Cao, Fuhua Tian, Qi Pan

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Yiru ShanDepartment of Oncology, Jiulongpo People's Hospital of Chongqing, Chongqing, P.R. China.
Guang YangDepartment of Urology Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China.
Qiuhong LuDepartment of Orthopaedics, Jiulongpo People's Hospital of Chongqing, Chongqing, P.R. China.
Xiangyu HuDepartment of Dermatology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, P.R. China.
Dongwei QiDepartment of Dermatology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, P.R. China.
Yehan ZhouDepartment of Pathology, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, P.R. China.
Yin XiaoDepartment of Oncology, Jiulongpo People's Hospital of Chongqing, Chongqing, P.R. China.
Li CaoDepartment of Patient Service Center, Jiulongpo People's Hospital of Chongqing, Chongqing, P.R. China.
Fuhua TianDepartment of Oncology, Jiulongpo People's Hospital of Chongqing, Chongqing, P.R. China.
Qi PanDepartment of Dermatology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, P.R. China.
Chongqing Jiulongpo People's Hospital · CNFirst People's Hospital of Chongqing · CNChongqing Medical University · CNUniversity of Electronic Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis is an iron-dependent form of cell death. In spite of its significance in pathogenesis and disease progression, ferroptotic signal transduction in HBV-HCC has not been fully explained. Here, four HCC open-source datasets were downloaded from the GEO repository. Cox regression and LASSO models were established to prioritize novel prognostic candidate biomarkers, and the results were verified

Indexed as

Carcinoma, HepatocellularFerroptosisLiver NeoplasmsAntigens, NeoplasmCell Cycle ProteinsCell LineCytoskeletal ProteinsHumansNF-E2-Related Factor 2PrognosisAntigens, NeoplasmCell Cycle ProteinsCep290 protein, humanCytoskeletal ProteinsNF-E2-Related Factor 2CEP290ferroptosishepatocellular carcinomaNrf2 signaling pathway

Identifiers

PMID35271462
PMCPMC8954978
OpenAlexW4220708891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.