SynthesisInternational journal of environmental research and public health2022
Povidone-Iodine as a Pre-Procedural Mouthwash to Reduce the Salivary Viral Load of SARS-CoV-2: A Systematic Review of Randomized Controlled Trials.
Synthesis in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Expert consensus on the use of oral antiseptics in oral surgery: Evidence-based clinical practice guidelines.Medicina oral, patologia oral y cirugia bucal · 2026Guideline
- Efficacy of Combining an Extraoral High-Volume Evacuator with Preprocedural Mouth Rinsing in Reducing Aerosol Contamination Produced by Ultrasonic Scaling.International journal of environmental research and public health · 2022Trial
- The Role of Saliva and Mouthwashes in the Detection and Reduction of Oral Viral Load: A Scoping Review.Viruses · 2025Article
- Mitigating aerosol contamination: strategies for contamination-free scaling.GMS hygiene and infection control · 2025Review
- Salivary iodide status as a measure of whole body iodine homoeostasis?The British journal of nutrition · 2024Review
- Lessons should be learned: Why did we not learn from the Spanish flu?SAGE open medicine · 2024Review
- HOCl Rapidly Kills Corona, Flu, and Herpes to Prevent Aerosol Spread.Journal of dental research · 2023Article
- Preprocedural Viral Load Effects of Oral Antiseptics on SARS-CoV-2 in Patients with COVID-19: A Systematic Review.Biomedicines · 2023Review
- Antiviral effect of cetylpyridinium chloride in mouthwash on SARS-CoV-2.Scientific reports · 2022Article
- Differences in microhardness and tensile strength of stainless steel temporary anchorage devices after exposure to fluoride, povidone-iodine, and chitosan solution.Journal of advanced pharmaceutical technology & researchArticle
- The Role of Poly Vinyl Pyrrolidone Iodine (PVP-I) in Preventing Cross-Infection during Dental Procedures: A Systematic Review in the COVID-19 Context.Journal of International Society of Preventive & Community DentistryReview
- Evaluation of Current Evidence on the Use of Oral Antiseptics Against SARS-CoV-2: A Narrative Review.Journal of International Society of Preventive & Community DentistryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of pre-procedural rinses has been investigated to reduce the number of viral particles and bacteria in aerosols, potentially decreasing the risk of cross-infection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during medical and dental procedures. This review aims to confirm whether there is evidence in the literature describing a reduction in salivary load of SARS-CoV-2 when povidone-iodine (PVP-I) is used as a pre-intervention mouthwash. An search of the MEDLINE, Embase, SCOPUS, and the Cochrane library databases was conducted. The criteria used followed the PRISMA
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.