Evidence map›Paper›PMID 35270461›Full record

ArticleInternational journal of environmental research and public health2022

Trends in the Epidemiology and Outcomes of Pneumocystis Pneumonia among Human Immunodeficiency Virus (HIV) Hospitalizations.

Kalaimani Elango, Mayuri Mudgal, Swetha Murthi, Prashanth Reddy Yella, Savan Nagrecha, Vedhapriya Srinivasan, Vijaykumar Sekar, Maria Koshy, Sathishkumar Ramalingam, Kulothungan Gunasekaran

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. The 2025 EQUALJAC-antimicrobial resistance · 2025
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  5. Low-dose atovaquone for prophylaxis ofEULAR rheumatology open · 2025
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  8. Observational
  9. Article
  10. Retracing the evolution ofMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  11. Article
  12. Article
  13. Chest X-ray Features of HIV-AssociatedOpen forum infectious diseases · 2024
    Article
  14. Article
  15. Article
  16. An Evaluation of the OLMJournal of fungi (Basel, Switzerland) · 2023
    Article
  17. Long-term Outcomes of Patients With HIV andOpen forum infectious diseases · 2023
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Kalaimani ElangoDivision of Cardiology, University of Nevada, 4505 S Maryland Pkwy, Las Vegas, NV 89154, USA.ORCID 0000-0003-1562-2411
Mayuri MudgalDepartment of Geriatric Medicine, Montefiore Medical Center, Wakefield Campus, 600 E 233rd Street Bronx, New York, NY 10466, USA.
Swetha MurthiDepartment of Endocrinology, Yuma Regional Medical Center, 2400 S Avenue A, Yuma, AZ 85364, USA.
Prashanth Reddy YellaDepartment of Internal Medicine, Yuma Regional Medical Center, 2400 S Avenue A, Yuma, AZ 85364, USA.ORCID 0000-0002-7495-1314
Savan NagrechaDepartment of Pharmacy, Yuma Regional Medical Center, 2400 S Avenue A, Yuma, AZ 85364, USA.
Vedhapriya SrinivasanDepartment of Internal Medicine, Suny Downstate Medical Center, New York, NY 11203, USA.
Vijaykumar SekarDepartment of Endocrinology, Lehigh Valley Health Center, 1243 S Cedar Crest Blvd, Allentown, PA 18103, USA.
Maria KoshyDepartment of Internal Medicine, Bridgeport Hospital, 267 Grant Street, Bridgeport, CT 06610, USA.
Sathishkumar RamalingamDepartment of Internal Medicine, Lovelace Medical Center, 601 Dr. Martin Luther King Jr. Avenue NE, Albuquerque, NM 87102, USA.
Kulothungan GunasekaranDepartment of Pulmonary Diseases and Critical Care, Yuma Regional Medical Center, 2400 S Avenue A, Yuma, AZ 85364, USA.ORCID 0000-0002-2872-1630
Regional Medical Center · USYuma Oncology Center · USBridgeport Hospital · USLehigh Valley Hospital · USLovelace Medical Center · USMontefiore Medical Center · USSUNY Downstate Health Sciences University · USUniversity of Nevada, Las Vegas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Pneumocystis Pneumonia (PCP) is a common opportunistic infection among people living with the human immunodeficiency virus (HIV). This study’s objective was to assess temporal trends in PCP epidemiology among hospitalized patients with HIV/AIDS in the US and to compare data for hospitalizations with HIV with PCP to those without PCP. Methods: The national inpatient sample (NIS) data were analyzed from 2002−2014. The discharge coding identified hospitalized patients with HIV or AIDS and with or without PCP. Results: We identified 3,011,725 hospitalizations with HIV/AIDS during the study period; PCP was present in 5% of the patients with a diagnosis of HIV. The rates of PCP progressively declined from 6.7% in 2002 to 3.5 % in 2014 (p < 0.001). Overall mortality in patients with HIV was 3.3% and was significantly higher in those with PCP than without PCP (9.9% vs. 2.9%; p < 0.001). After adjusting for demographics and other comorbidities, PCP had higher odds of hospital mortality 3.082 (OR 3.082; 95% CI, 3.007 to 3.159; p < 0.001). Conclusion: From 2002 to 2014, the rate of PCP in HIV patients has decreased significantly in the United States but is associated with substantially higher mortality.

Indexed as

HIV InfectionsPneumonia, PneumocystisHIVHospitalizationHospital MortalityHumansUnited Statesantiretroviral therapyepidemiologyHIVhuman immunodeficiency virusopportunistic infectionPCPPneumocystis jiroveciiPneumocystis pneumoniapneumonia

Identifiers

PMID35270461
PMCPMC8910294
OpenAlexW4220764791

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.