Evidence map›Paper›PMID 35270303›Full record

ArticleInternational journal of environmental research and public health2022

Human Papillomavirus Self-Sampling for Primary Cervical Cancer Screening in Under-Screened Women in Hong Kong during the COVID-19 Pandemic.

Siew-Fei Ngu, Lesley S K Lau, Justin Li, Grace C Y Wong, Annie N Y Cheung, Hextan Y S Ngan, Karen K L Chan

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Siew-Fei NguDepartment of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
Lesley S K LauDepartment of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
Justin LiLi Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.ORCID 0000-0003-2758-5363
Grace C Y WongThe Family Planning Association of Hong Kong, Hong Kong.
Annie N Y CheungDepartment of Pathology, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
Hextan Y S NganDepartment of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
Karen K L ChanDepartment of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Hong Kong.ORCID 0000-0002-4034-7469
Queen Mary Hospital · CNFamily Planning Association of Hong Kong · CNUniversity of Hong Kong · HK

Funding

Karen Leung Foundation N/ARoche Diagnostic N/A
6 · The paper itself

Abstract

The aim of this study was to assess the effectiveness of HPV self-sampling for cervical cancer screening and the best means of service delivery, with a specific focus on under-screened women, particularly during the COVID-19 pandemic. Using three arms of service delivery (social media, school outreach and underserved outreach), we recruited under-screened women aged 30-65 years from two population groups: the general public and specific underserved communities, from whom self-sampled specimens and optional clinician-sampled cervical specimens were obtained for HPV testing. A total of 521 self-sampling kits were distributed, of which 321 were returned, giving an overall uptake rate of 61.6%. The response rate was higher in the face-to-face underserved outreach (65.5%) compared to social media (22.8%) and school outreach (18.2%). The concordance for HPV detection between self-sampled and clinician-sampled specimens was 90.2% [95% confidence interval (CI) 85.1-93.8%; Cohen's kappa 0.59 (95% CI 0.42-0.75)]. Overall, 89.2% of women were willing to have self-sampling again. In conclusion, HPV self-sampling is an effective method for cervical cancer screening and can be considered as an option, particularly in women who are reluctant or unable to attend regular screening. Various service deliveries could be considered to increase participation in cervical cancer screening.

Indexed as

AlphapapillomavirusCOVID-19Papillomavirus InfectionsUterine Cervical NeoplasmsAdultAgedEarly Detection of CancerFemaleHong KongHumansMiddle AgedPandemicsPapillomaviridaeSARS-CoV-2Self Carecervical cancer screeningCOVID-19 pandemichuman papillomavirus (HPV)self-sampling

Identifiers

PMID35270303
PMCPMC8910259
OpenAlexW4213448712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.