ArticleInternational journal of molecular sciences2022
Development and Characterization of Gentamicin-Loaded Arabinoxylan-Sodium Alginate Films as Antibacterial Wound Dressing.
Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Article
- Moderation of cross linkage of sodium alginate-polyethylene oxide films loaded with natamycin for treatment of Aspergillus fumigatus keratitis.Journal of materials science. Materials in medicine · 2025Article
- Assessing polylactic acid nanofibers with cellulose and chitosan nanocapsules loaded with chamomile extract for treating gram-negative infections.Scientific reports · 2024Article
- Preparation and characterization of a ciprofloxacin-loaded nanoparticles incorporated polymeric film dressing.RSC advances · 2024Article
- Recycling of wheat gluten wastewater: Recovery of arabinoxylan and application of its film in cherry and strawberry preservation.Food chemistry: X · 2024Article
- Recent Advances in Biomedical Applications of Mannans and Xylans.Current drug targets · 2024Review
- Advances of antimicrobial dressings loaded with antimicrobial agents in infected wounds.Frontiers in bioengineering and biotechnology · 2024Review
- Optimization of the Green Extraction of Red Araçá (Molecules (Basel, Switzerland) · 2023Article
- Biopolymers in Drug and Gene Delivery Systems.International journal of molecular sciences · 2023Article
- Structural and Physical Properties of Alginate Pretreated by High-Pressure Homogenization.Polymers · 2023Article
- Films for Wound Healing Fabricated Using a Solvent Casting Technique.Pharmaceutics · 2023Review
- Alginate-Based Materials Loaded with Nanoparticles in Wound Healing.Pharmaceutics · 2023Review
- Local Drug Delivery Strategies towards Wound Healing.Pharmaceutics · 2023Review
- In Vitro and In Vivo Characterization Methods for Evaluation of Modern Wound Dressings.Pharmaceutics · 2022Review
- Arabinoxylan-Carboxymethylcellulose Composite Films for Antibiotic Delivery to Infected Wounds.Polymers · 2022Article
- Formulation and Evaluation of Novel Film Wound Dressing Based on Collagen/Microfibrillated Carboxymethylcellulose Blend.Pharmaceutics · 2022Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Biopolymer-based antibacterial films are attractive materials for wound dressing application because they possess chemical, mechanical, exudate absorption, drug delivery, antibacterial, and biocompatible properties required to support wound healing. Herein, we fabricated and characterized films composed of arabinoxylan (AX) and sodium alginate (SA) loaded with gentamicin sulfate (GS) for application as a wound dressing. The FTIR, XRD, and thermal analyses show that AX, SA, and GS interacted through hydrogen bonding and were thermally stable. The AXSA film displays desirable wound dressing characteristics: transparency, uniform thickness, smooth surface morphology, tensile strength similar to human skin, mild water/exudate uptake capacity, water transmission rate suitable for wound dressing, and excellent cytocompatibility. In Franz diffusion release studies, >80% GS was released from AXSA films in two phases in 24 h following the Fickian diffusion mechanism. In disk diffusion assay, the AXSA films demonstrated excellent antibacterial effect against E.coli, S. aureus, and P. aeruginosa. Overall, the findings suggest that GS-loaded AXSA films hold potential for further development as antibacterial wound dressing material.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.