Evidence map›Paper›PMID 35270025›Full record

ReviewInternational journal of molecular sciences2022

Cosmeceutical Therapy: Engaging the Repercussions of UVR Photoaging on the Skin's Circadian Rhythm.

Camille Keisha Mahendra, Hooi-Leng Ser, Priyia Pusparajah, Thet Thet Htar, Lay-Hong Chuah, Wei Hsum Yap, Yin-Quan Tang, Gokhan Zengin, Siah Ying Tang, Wai Leng Lee and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Regulation of dermal circadian pathways by a novel topical formulation.International journal of cosmetic science · 2025
    Article
  3. The Influence of Circadian Rhythms on DNA Damage Repair in Skin Photoaging.International journal of molecular sciences · 2024
    Review
  4. Research Progress on Skin Aging and Active Ingredients.Molecules (Basel, Switzerland) · 2023
    Review
  5. Review
  6. The Prospects ofAntioxidants (Basel, Switzerland) · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Camille Keisha MahendraBiofunctional Molecule Exploratory Research Group, School of Pharmacy, Monash University Malaysia, Bandar Sunway 47500, Malaysia.ORCID 0000-0002-8809-7454
Hooi-Leng SerNovel Bacteria and Drug Discovery Research Group, Microbiome and Bioresource Research Strength Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.ORCID 0000-0003-3815-7436
Priyia PusparajahMedical Health and Translational Research Group, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.
Thet Thet HtarBiofunctional Molecule Exploratory Research Group, School of Pharmacy, Monash University Malaysia, Bandar Sunway 47500, Malaysia.ORCID 0000-0001-6193-1237
Lay-Hong ChuahBiofunctional Molecule Exploratory Research Group, School of Pharmacy, Monash University Malaysia, Bandar Sunway 47500, Malaysia.ORCID 0000-0001-8283-0849
Wei Hsum YapSchool of Biosciences, Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya 47500, Malaysia.ORCID 0000-0001-8116-6018
Yin-Quan TangSchool of Biosciences, Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya 47500, Malaysia.ORCID 0000-0001-7327-2830
Gokhan ZenginPhysiology and Biochemistry Research Laboratory, Department of Biology, Science Faculty, Selcuk University, Konya 42130, Turkey.ORCID 0000-0001-6548-7823
Siah Ying TangChemical Engineering Discipline, School of Engineering, Monash University Malaysia, Bandar Sunway 47500, Malaysia.ORCID 0000-0001-5734-0194
Wai Leng LeeSchool of Science, Monash University Malaysia, Bandar Sunway 47500, Malaysia.ORCID 0000-0002-0036-2859
Kai Bin LiewFaculty of Pharmacy, University of Cyberjaya, Cyberjaya 63000, Malaysia.
Long Chiau MingPengiran Anak Puteri Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong BE1410, Brunei.ORCID 0000-0002-6971-1383
Bey Hing GohBiofunctional Molecule Exploratory Research Group, School of Pharmacy, Monash University Malaysia, Bandar Sunway 47500, Malaysia.ORCID 0000-0003-1006-3649
Monash University Malaysia · MYTaylor's University · MYSelçuk University · TRUniversiti Brunei Darussalam · BNUniversity of Cyberjaya · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sunlight is an important factor in regulating the central circadian rhythm, including the modulation of our sleep/wake cycles. Sunlight had also been discovered to have a prominent influence on our skin's circadian rhythm. Overexposure or prolonged exposure to the sun can cause skin photodamage, such as the formation of irregular pigmentation, collagen degradation, DNA damage, and even skin cancer. Hence, this review will be looking into the detrimental effects of sunlight on our skin, not only at the aspect of photoaging but also at its impact on the skin's circadian rhythm. The growing market trend of natural-product-based cosmeceuticals as also caused us to question their potential to modulate the skin's circadian rhythm. Questions about how the skin's circadian rhythm could counteract photodamage and how best to maximize its biopotential will be discussed in this article. These discoveries regarding the skin's circadian rhythm have opened up a completely new level of understanding of our skin's molecular mechanism and may very well aid cosmeceutical companies, in the near future, to develop better products that not only suppress photoaging but remain effective and relevant throughout the day.

Indexed as

CosmeceuticalsSkin AgingSkin DiseasesCircadian RhythmHumansSkinCosmeceuticalsapoptosiscircadian rhythmcollagen degradationcosmeticsDNA damagemelatoninnatural productphotoagingpigmentationultraviolet rays

Identifiers

PMID35270025
PMCPMC8911461
OpenAlexW4221083855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.